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This study employed metabolomic profiling technologies, to identify metabolites (small molecules) in blood which are found at different levels in vaccinated compared to non-vaccinated animals exposed to virus.
2018-07-13 | MTBLS456 | MetaboLights

Chlamydia trachomatis, an intracellular pathogen, is recognized as the most common sexually transmitted bacterial infection among women worldwide. Chlamydia infections can lead to undesirable clinical outcomes, including pelvic inflammatory disease and infertility. Recently, the gut has been...

2025-11-07 | MTBLS12603 | MetaboLights
Three groups of German Landrace piglets were vaccinated with tetanus toxoid. Transcriptome profiles of PBMC were analysed from blood samples taken 0, 2, 4, 8, 24 and 75 hours after a first vaccination and 0, 2, 4, 8, 24 and 75 hours as well as 14 d after a second vaccination on day 14. pair wise com...
ORGANISM(S): Sus scrofa 
In this study we performed RNA-seq to identify human transcriptomic signatures associated with antibody responses to an oral cholera vaccine. We isolated total RNA from peripheral blood mononuclear cells of vaccinated volunteers who following two priming oral immunisations, had either strong or no a...
ORGANISM(S): Homo sapiens 
As the development of a dengue vaccine is ongoing, we simulate an hypothetical vaccine as an extra protection to the population. In a first phase, the vaccination process is studied as a new compartment in the model, and different ways of distributing the vaccines investigated: pediatric and random ...
2020-03-20 | MODEL2003190001 | BioModels
Restif2007 - Vaccination invasion This model is described in the article: Vaccination and the dynamics of immune evasion. Restif O, Grenfell BT. J R Soc Interface 2007 Feb; 4(12): 143-153 Abstract: Vaccines exert strong selective pressures on pathogens, favouring ...
2024-09-02 | BIOMD0000000294 | BioModels
Amyloid-beta (Aβ) deposition is an initiating factor in Alzheimer´s disease (AD). Microglia are the brain immune cells that surround and phagocytose Aβ, but their phagocytic capacity declines in AD. This is in agreement with studies that associate AD risk loci with genes regulating phagocytic functi...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-09 | PXD038665 | Pride
Vaccination triggers the production of antigen-specific antibodies, including IgG. IgG molecules are glycosylated at the Fc region, and these glycan modifications markedly influence Fc receptor binding and downstream immune functions. Notably, infections with enveloped viruses such as SARS-CoV-2 can...
ORGANISM(S): Mesocricetus auratus (Golden hamster) Macaca mulatta (Rhesus macaque) 
2026-03-11 | PXD068257 | Pride
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