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RNA-sequencing of gastric cancer PDX mice model after treated with CUS
The interaction between cancer and depressive disorder remains unclear. In this study, we obtained patient data from TCGA and MDD-related (Major Depressive Disorder) genes from the GEO database and the sequencing data of the PDX model with chronic unpredictable stress (CUS). Molecular subtypes and a...
ORGANISM(S): Homo sapiens 
2024-07-19 | GSE262056 | GEO
Genomics
Assessing PEG/CuS-NPs Toxicity: Impact on Gut Microbiota in Rat Model
The resin glycoside Cus-1, a cuscutae extract, ameliorates oligozoospermia via an aquaporin-driven p38 MAPK/SAT1/GPX4 axis that suppresses ferroptosis and restores spermatogenesis
This study employed 1H-NMR-guided isolation to rapidly pinpoint, purify and elucidate the on-the-map metabolite resin glycosides“Cus-1” from the Cuscuta chinensis Lam. phenotype, and subsequently interrogated its remedial value in a busulfan (BUS)-induced mouse model of oligozoospermia.
ORGANISM(S): Mus musculus 
2026-06-30 | GSE336587 | GEO
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