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TranscriptomicsPrimate transcript and protein expression levels evolve under compensatory selection pressures
Variation in gene regulation is thought to have played an important role in the evolution of primates, and many studies have documented differences in mRNA expression levels across primate species. However, it is not yet known to what extent measurements of divergence in mRNA levels reflect divergen...
ORGANISM(S): Pan troglodytes 
2013-10-17 | E-GEOD-49682 | biostudies-arrayexpress
TranscriptomicsThe Combination of a Genome-Wide Association Study of Lymphocyte Count and Analysis of Gene Expression Data Reveals Novel Asthma Candidate Genes
Recent genome-wide association studies (GWAS) have identified a number of novel genetic associations with complex human diseases. In spite of these successes, results from GWAS generally explain only a small proportion of disease heritability, an observation termed the M-bM-^@M-^\missing heritabilit...
ORGANISM(S): Homo sapiens 
2012-02-01 | E-GEOD-30697 | biostudies-arrayexpress
TranscriptomicsRegulatory element copy number differences shape primate expression profiles.
Gene expression differences are shaped by selective pressures and contribute to phenotypic differences between species. We identified 964 copy number differences (CNDs) of conserved sequences across 3 primate species and examined their potential effects on gene expression profiles. Samples with copy...
ORGANISM(S): Pan troglodytes 
2012-08-02 | E-GEOD-38572 | biostudies-arrayexpress
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