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TranscriptomicsGene expression in cutaneous lupus erythematosus
Lesional skin biopsies were taken from patients with active, untreated lupus skin disease (chronic discoid lupus erythematosus, CDLE, n=6; subacute cutaneous lupus erythematosus, SCLE, n=5). Healthy control specimens (HC) were obtained from healthy skin of 5 patients undergoing plastic surgery. In ...
ORGANISM(S): Homo sapiens 
2017-02-24 | E-MTAB-5542 | biostudies-arrayexpress
ProteomicsCutaneous Lupus Erythematosus: proteomics salivary profiling
Background: Cutaneous lupus erythematosus (CLE) is a complex autoimmune condition with limited data on its molecular underpinnings. Saliva, as plasma filtrate fluid may be a promising tool for biomarkers discovery, since it is an easily accessible biofluid. This study aimed to characterize the saliv...
ORGANISM(S): Homo sapiens (Human) 
2025-12-22 | PXD064580 | Pride
Cutaneous lupus erythematosus Proteomics Saliva 
TranscriptomicsRNA-seq of blood from donors with connective tissue diseases in the Lupus Extended Phenotype Cohort
The connective tissue diseases (CTDs) are group of inflammatory disorders with overlapping clinical and serological manifestations. We have undertaken Lupus Extended Phenotype (LEAP) study in of a cohort of adult patients with CTDs, namely systemic lupus erythematosus, Sjogren's syndrome, mixed and ...
ORGANISM(S): Homo sapiens 
2019-06-05 | E-MTAB-7080 | biostudies-arrayexpress
GenomicsSpatial transcriptomics of Cutaneous and Systemic Lupus Erythematosus skin
Spatial transcriptomics of Cutaneous and Systemic Lupus Erythematosus skin
PRJNA758013 | ENA
GenomicsGene expression analysis in complex canine chronic cutaneous lupus erythematosus (CCLE)
Gene expression analysis in complex canine chronic cutaneous lupus erythematosus (CCLE)
PRJNA747302 | ENA
GenomicsGene expression analysis in canine discoid/chronic lupus erythematosus, mucocutaneous lupus erythematosus and pyoderma
Gene expression analysis in canine discoid/chronic lupus erythematosus, mucocutaneous lupus erythematosus and pyoderma
PRJNA672714 | ENA
TranscriptomicsSpatial transcriptomics of Cutaneous and Systemic Lupus Erythematosus skin
We performed spatial transcriptomics on a case series of different clinical subtypes of cutaneous lupus erythematosus including acute cutaneous lupus erythematosus (malar rash, systemic lupus erythematosus). Our goals were to (1) determine which differentially expressed genes (DEGs) could be attribu...
ORGANISM(S): Homo sapiens 
2021-10-01 | GSE182825 | GEO
TranscriptomicsGene expression analysis in canine discoid/chronic lupus erythematosus, mucocutaneous lupus erythematosus and pyoderma
We performed a comparative immunology case study of client-owned dogs to determine if immune and skin gene expression profiles in spontaneous canine cutaneous lupus erythematosus mirror those observed in human cutaneous lupus.
ORGANISM(S): Canis lupus familiaris 
2022-03-23 | GSE160260 | GEO
UnknownSystemic lupus erythematosus is a risk factor for having multiple subtypes of cutaneous lupus erythematosus.
Not available
S-EPMC11780969 | biostudies-literature
TranscriptomicsGene expression analysis in complex canine chronic cutaneous lupus erythematosus (CCLE)
We performed a comparative immunology case study of client-owned dogs to determine if immune and skin gene expression profiles in spontaneous canine chronic cutaneous lupus erythematosus (CCLE) with concomitant systemic autoimmunity mirror those observed in human CCLE.
ORGANISM(S): Canis lupus familiaris 
2022-02-11 | GSE180276 | GEO
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