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TranscriptomicsHuman transcriptome pattern of primary cutaneous lesions from patients with localized cutaneous leishmaniasis and mucosal leishmaniasis
We evaluated the trancriptome of primary cutaneous leisions caused by infection with Leishmania braziliensis. mRNA-seq technique was used to study the trancriptome of both host and parasite. A total of 10 samples was obtained from primary skin ulcers of two extreme clinical forms of American tegumen...
ORGANISM(S): Homo sapiens 
2012-10-24 | E-GEOD-33601 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human skin biopsies in cutaneous T-cell lymphoma
Cutaneous T cell lymphoma (CTCL) is defined by infiltration of activated and malignant T cells in skin. The clinical manifestations and prognosis in CTCL are highly variable. In this study, we hypothesized that gene expression analysis in lesional skin biopsies can improve understanding of the disea...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9479 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiles of cutaneous B-cell lymphoma
We studied gene expression profiles of 17 cutaneous B-cell lymphomas that were collected with 4-6 millimeter skin punch biopsies. We also included tissue from 2 cases of mycosis fungoides (MF), 3 normal skin biopsies and 3 tonsils to create a framework for further interpretation. A hierarchical clus...
ORGANISM(S): Homo sapiens 
2005-12-16 | E-GEOD-3827 | biostudies-arrayexpress
TranscriptomicsKGF effects on cutaneous SCC cells
Keratinocyte growth factor (KGF, fibroblast growth factor-7) is a fibroblast-derived mitogen, which stimulates proliferation of epithelial cells. The expression of KGF by dermal fibroblasts is induced following injury and it promotes wound repair. However, the role of KGF in cutaneous carcinogenesis...
ORGANISM(S): Homo sapiens 
2012-05-01 | E-GEOD-34652 | biostudies-arrayexpress
TranscriptomicsKey differences identified between actinic keratosis and cutaneous squamous cell carcinoma by transcriptome profiling
Cutaneous squamous cell carcinoma (cSCC) is one of the most common malignancies in fair skinned populations worldwide and its incidence is increasing. Despite previous observations of multiple genetic abnormalities in cSCC, the oncogenic process remains elusive. The purpose of this study was to inve...
ORGANISM(S): Homo sapiens 
2014-01-21 | E-GEOD-45216 | biostudies-arrayexpress
ProteomicsTAp63-regulated microRNAs suppress cutaneous squamous cell carcinoma
TAp63 is a transcription factor belonging to the p53 family with important tumor suppressive functions. We show that TAp63-/- mice exhibit an increased susceptibility to UVR-induced cutaneous squamous cell carcinoma (cuSCC). These tumors showed global disruption of miRNA and mRNA expression when com...
ORGANISM(S): Homo sapiens (Human) 
2020-07-07 | PXD014261 | Pride
Cutaneous squamous cell carcinoma Microrna P63 Expression proteomics 
UnknownMolecular signatures of anthroponotic cutaneous leishmaniasis in the lesions of patients infected with Leishmania tropica.
Not available
S-EPMC7529897 | biostudies-literature
UnknownPyroptosis-Related Gene Signatures Can Robustly Diagnose Skin Cutaneous Melanoma and Predict the Prognosis.
Not available
S-EPMC8313829 | biostudies-literature
ProteomicsRobust dimethyl-based multiplex-DIA doubles single-cell proteome depth via a reference channel
Single-cell proteomics aims to characterize biological function and heterogeneity at the level of proteins in an unbiased manner. It is currently limited in proteomic depth, throughput, and robustness, which we address here by a streamlined multiplexed workflow using data-independent acquisition (mD...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-12-22 | MSV000090956 | MassIVE
GenomicsPeripheral Blood Transcriptomic Signatures Associated with Cutaneous Radiation Injury in Cancer Patients Undergoing Radiotherapy
Peripheral Blood Transcriptomic Signatures Associated with Cutaneous Radiation Injury in Cancer Patients Undergoing Radiotherapy
PRJNA1480763 | ENA
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