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ProteomicsSystematic mapping of the adipocyte plasma membrane proteome reveals KCC1 and PIT2 as novel insulin-responsive transporters
The plasma membrane (PM) is a dynamic interface that integrates environmental cues with cellular responses. Insulin is known to remodel the PM primarily by stimulating the translocation of glucose transporter type 4 (GLUT4), but the full scope of this regulation remains poorly defined. Here, we perf...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-23 | PXD068305 | Pride
UnknownSomatic mutations predict poor outcome in patients with myelodysplastic syndrome after hematopoietic stem-cell transplantation.
Not available
S-EPMC4207878 | biostudies-literature
UnknownOdd and Even Numbered Ferric Wheels.
Not available
S-EPMC10625049 | biostudies-literature
UnknownHealth, functioning, and disability in older adults--present status and future implications.
Not available
S-EPMC4882096 | biostudies-literature
TranscriptomicsMolecular Signatures of Fetal and Adult Prostate Stem Cells
The global gene expression profiles of adult and fetal murine prostate stem cells were determined to define common and unique regulators whose misexpression might play a role in the development of prostate cancer. A distinctive core of transcriptional regulators common to both fetal and adult primit...
ORGANISM(S): Mus musculus 
2009-04-29 | E-GEOD-15580 | biostudies-arrayexpress
TranscriptomicsUGE and UGM Reveal Novel Signaling Pathways and Ligand-Receptor Interactions in the Primitive Prostate Stem Cell Niche
We isolated fetal murine urogenital sinus epithelium and urogenital sinus mesenchyme and determined their global gene expression profiles to define their differentially expressed regulators. To distinguish gene expression patterns that are shared by other developing epithelial/mesenchymal compartmen...
ORGANISM(S): Mus musculus 
2010-08-29 | E-GEOD-17797 | biostudies-arrayexpress
ProteomicsDeletion of the mitochondrial peptidase miPEP in adipose tissue protects against obesity and insulin resistance by increasing adaptive thermogenesis
Mitochondria are pivotal for cellular metabolism, serving as sources and targets of nutrient intermediates from converging metabolic pathways. Here, we demonstrate that insulin resistance leads to a marked alteration in the mitochondrial proteome of adipocytes. Analysis across multiple insulin resis...
ORGANISM(S): Mus musculus (Mouse) 
2024-08-10 | PXD051606 | Pride
Insulin resistance Mipep Thermogenesis Adipose Mitochondria 
UnknownSpecialist use among privately insured children with disabilities.
Not available
S-EPMC11250397 | biostudies-literature
UnknownOmidubicel vs standard myeloablative umbilical cord blood transplantation: results of a phase 3 randomized study.
Not available
S-EPMC9710469 | biostudies-literature
TranscriptomicsTreatment of myeloma cell lines with the bromodomain inhibitor I-BET151
KMS12BM and H929 myeloma cells were treated in vitro with either I-BET151 1uM or vehicle (DMSO) for 6 hours (n=3 independent experiments for each cell line). Total RNA was extracted from H929 and KMS12BM cells using the RNeasy Mini kit (Qiagen). Genomic DNA contamination was eliminated using colum...
ORGANISM(S): Homo sapiens 
2013-12-22 | E-MTAB-2122 | biostudies-arrayexpress
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