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Memory T cells are important for protective immunity against infectious microorganisms. Such protection is achieved by cooperative action of memory T cell populations that differ in their tissue localization and functionality. We report on the identification of the fractalkine receptor CX3CR1 as mar...
ORGANISM(S): Mus musculus 
Memory T cells are important for protective immunity against infectious microorganisms. Such protection is achieved by cooperative action of memory T cell populations that differ in their tissue localization and functionality. We report on the identification of the fractalkine receptor CX3CR1 as mar...
ORGANISM(S): Homo sapiens 
The aging brain shows changes in microglial function, morphology, and phenotype, indicating chronic microglial activation. CX3CR1 is crucial for microglial chemotaxis, phagocytosis, and activation. However, its exact role in the aging brain is not well understood. In this study, we examined the expr...
ORGANISM(S): Mus musculus (Mouse) 
2025-07-05 | PXD058961 | Pride
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
We hypothesize that under homeostatic as well as inflammatory conditions circulating monocytes and/or their bone marrow-derived progenitors might contribute to the replenishment of CD103+ and CD103- DC in lymphoid and non-lymphoid compartments. To that end, bone marrow cells from CX3CR1+/gfp C57BL/6...
ORGANISM(S): Mus musculus 
Transcriptional profiling of mice decidual CX3CR1+ and CX3CR1- primed CD8 T cells
Cx3cr1-deficient microglia exhibit a premature aging transcriptome
Cx3cr1-deficient microglia exhibit a premature aging transcriptome
GFP+CD45+CD11b+ cells were isolated from from heterozygous adult Cx3cr1-GFP/+ mouse hearts, spleens and brains by fluorescence activated cell sorting to prepare RNA for gene array analysis.
Three independently isolated populations GFP+ (CD45+CD11b+) cells for each tissue were used as replicates.
ORGANISM(S): Mus musculus 
Chromatin accessibility landscapes of CX3CR1+ effector , CX3CR1- Ly108- exhausted, or Ly108+ progenitor CD8 T cells during chronic viral infection.
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