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GenomicsThe ELK3-CXCL16 axis regulates NK cell cytotoxicity via the chemotactic activity of CXCL16 in TNBC
The ELK3-CXCL16 axis regulates NK cell cytotoxicity via the chemotactic activity of CXCL16 in TNBC
PRJNA860173 | ENA
ProteomicsThe secretome profiling of a pediatric airway epithelium infected with hRSV identified aberrant apical/basolateral trafficking and novel immune modulating (CXCL6, CXCL16, CSF3) and antiviral (CEACAM1) proteins.
The respiratory epithelium comprises polarized cells at the interface between the environment and airway tissues. Polarized apical and basolateral protein secretions are a feature of airway epithelium homeostasis. Human respiratory syncytial virus (hRSV) is a major human pathogen that primarily targ...
ORGANISM(S): Homo sapiens (Human) 
2020-02-25 | PXD013661 | Pride
Cxcl16 Secretome directionality Respiratory syncytial virus Well-differentiated pediatric bronchial epithelial cells (wd-pbecs) Ceacam1 Quantitative proteomics Cxcl6 Csf3 
TranscriptomicsThe ELK3-CXCL16 axis regulates NK cell cytotoxicity via the chemotactic activity of CXCL16 in TNBC
Background Triple-negative breast cancer (TNBC) is the most challenging subtype of breast cancer because of its aggressive behavior and the limited therapeutic strategies available. In the last decade, immunotherapy has become a promising treatment to prolong survival in advanced solid cancers inclu...
ORGANISM(S): Homo sapiens 
2022-07-20 | GSE208584 | GEO
GenomicsCXCL16-driven CD4+ T cells orchestrate immunosurveillance against MHC-I-deficient tumors
CXCL16-driven CD4+ T cells orchestrate immunosurveillance against MHC-I-deficient tumors
PRJNA1294882 | ENA
UnknownCXCL16 Promotes Gastric Cancer Tumorigenesis via ADAM10-Dependent CXCL16/CXCR6 Axis and Activates Akt and MAPK Signaling Pathways.
Not available
S-EPMC8326113 | biostudies-literature
UnknownELK3-CXCL16 axis determines natural killer cell cytotoxicity via the chemotactic activity of CXCL16 in triple negative breast cancer.
Not available
S-EPMC10026901 | biostudies-literature
UnknownElevated plasma levels of CXCL16 in severe COVID-19 patients.
Not available
S-EPMC8801318 | biostudies-literature
UnknownAtherogenic lipids induce high-density lipoprotein uptake and cholesterol efflux in human macrophages by up-regulating transmembrane chemokine CXCL16 without engaging CXCL16-dependent cell adhesion.
Not available
S-EPMC2740747 | biostudies-literature
UnknownCXCR6-CXCL16 Axis Promotes Breast Cancer by Inducing Oncogenic Signaling.
Not available
S-EPMC8306453 | biostudies-literature
GenomicsCXCR6+ CD4+ Tissue-Resident Memory T Cells Orchestrate Relapse in Allergic Dermatitis via CXCL16-Dependent Persistence
CXCR6+ CD4+ Tissue-Resident Memory T Cells Orchestrate Relapse in Allergic Dermatitis via CXCL16-Dependent Persistence
PRJNA1277745 | ENA
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