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MetabolomicsCEACAM1 Targets ABCA1 to mediate Atrial Fibrillation by regulating Lipophagy-Dependent Ferroptosis

Atrial fibrillation（AF） is one of the most common arrhythmias, imposing a significant burden on individuals due to its association with cerebrovascular events. The mechanisms underlying AF involve cardiac structural remodeling, electrical remodeling, and metabolic remodeling, with oxidative ...

2025-11-12 | MTBLS13308 | MetaboLights
GenomicsRNA-seq of CEACAM1- and CEACAM1+ regulatory T cells from tumor in patients with renal cell carcinoma
RNA-seq of CEACAM1- and CEACAM1+ regulatory T cells from tumor in patients with renal cell carcinoma
PRJNA899835 | ENA
TranscriptomicsRNA-seq of CEACAM1- and CEACAM1+ regulatory T cells from tumor in patients with renal cell carcinoma
We aimed to analyze the transcriptomic differences between CEACAM1- and CEACAM1+ regulatory T cells from tumor.
ORGANISM(S): Homo sapiens 
2023-01-25 | GSE217613 | GEO
ProteomicsThe secretome profiling of a pediatric airway epithelium infected with hRSV identified aberrant apical/basolateral trafficking and novel immune modulating (CXCL6, CXCL16, CSF3) and antiviral (CEACAM1) proteins.
The respiratory epithelium comprises polarized cells at the interface between the environment and airway tissues. Polarized apical and basolateral protein secretions are a feature of airway epithelium homeostasis. Human respiratory syncytial virus (hRSV) is a major human pathogen that primarily targ...
ORGANISM(S): Homo sapiens (Human) 
2020-02-25 | PXD013661 | Pride
Cxcl16 Secretome directionality Respiratory syncytial virus Well-differentiated pediatric bronchial epithelial cells (wd-pbecs) Ceacam1 Quantitative proteomics Cxcl6 Csf3 
GenomicsIntestine epithelial Ceacam1 deficiency prevents steroid-refractory acute gut graft-versus-host disease
Intestine epithelial Ceacam1 deficiency prevents steroid-refractory acute gut graft-versus-host disease
PRJNA1119637 | ENA
TranscriptomicsRegulation of the epithelial adhesion molecule CEACAM1 is essential for palate formation.
Cleft palate results from a mixture of genetic and environmental factors and occurs when the bilateral palatal shelves fail to fuse. The objective of this study was to search for new genes involved in mouse palate formation. Gene expression of murine embryonic palatal tissue was analyzed at the vari...
ORGANISM(S): Mus musculus 
2013-01-23 | E-GEOD-43651 | biostudies-arrayexpress
TranscriptomicsRegulation of the epithelial adhesion molecule CEACAM1 is essential for palate formation.
Cleft palate results from a mixture of genetic and environmental factors and occurs when the bilateral palatal shelves fail to fuse. The objective of this study was to search for new genes involved in mouse palate formation. Gene expression of murine embryonic palatal tissue was analyzed at the vari...
ORGANISM(S): Mus musculus 
2013-01-23 | GSE43651 | GEO
TranscriptomicsCEACAM1 is an inhibitory macrophage immune checkpoint via homophilic engagement
Macrophage-mediated tumor cell phagocytosis is an important component of tumor immunosurveillance, yet the mechanisms by which tumors evade macrophage-mediated clearance remain incompletely understood. In this study, we identified CEACAM1 as an inhibitory macrophage immune checkpoint that suppresses...
ORGANISM(S): Mus musculus 
2026-10-06 | GSE346947 | GEO
GenomicsEffect of ablation of CEACAM1 on gene expression in human regulatory T cells
Effect of ablation of CEACAM1 on gene expression in human regulatory T cells
PRJNA1080673 | ENA
TranscriptomicsExpression profile of Ceacam1 downstream genes in NSC and NSCL61
To identify Ceacam1 downstream factors, we compared gene expressions between NSCs and Ceacam1L-expressing NSC and between NSCL61 and Ceacam1shRNA-expressing NSCL61. We established Ceacam1L-expressing NSC and Ceacam1shRNA-expressing NSCL61s. We think that genes, which are differently expressed betwee...
ORGANISM(S): Mus musculus 
2015-11-04 | E-GEOD-70023 | biostudies-arrayexpress
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