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ProteomicsCharacterizing T-cell immunopeptidomes
Imunopeptidomes promise novel surface markers as ideal targets for immunotherapies, but their characterization by mass spectrometry (MS) remains challenging. Until recently, cell numbers exceeding 1.0xE9 were needed for reasonably deep immunopeptidome surveys of at least 1,000 HLA ligands. Such limi...
ORGANISM(S): Homo sapiens (Human) 
2018-03-08 | PXD007860 | Pride
Human Antigen presentation T cell Mhc Orbitrap 
UnknownFollicular lymphoma B cells induce the conversion of conventional CD4+ T cells to T-regulatory cells.
Not available
S-EPMC2631275 | biostudies-literature
UnknownCD81 costimulation skews CAR transduction toward naive T cells.
Not available
S-EPMC8812682 | biostudies-literature
ProteomicsAntigen Presentation Profiling Reveals T-cell Recognition of Lymphoma Immunoglobulin Neoantigens
Cancer somatic mutations can generate neoantigens that distinguish malignant from normal cells. Such neoantigens have been implicated in response to immunotherapies including immune checkpoint blockade, yet their identification and validation remains challenging. Here we discover neoantigens in hu...
ORGANISM(S): Homo sapiens (Human) 
2017-03-27 | PXD004746 | Pride
Human Mhc Mantle cell lymphoma Antigen presentation Ltq orbitrap elite 
ProteomicsAntigen Presentation Profiling Reveals T-cell Recognition of Lymphoma Immunoglobulin Neoantigens
Cancer somatic mutations can generate neoantigens that distinguish malignant from normal cells. Such neoantigens have been implicated in response to immunotherapies including immune checkpoint blockade, yet their identification and validation remains challenging. Here we discover neoantigens in huma...
ORGANISM(S): Homo sapiens (Human) 
2017-03-27 | PXD005704 | Pride
Human Antigen presentation Ltq orbitrap elite Mhc class i 
UnknownT-Cell Immunopeptidomes Reveal Cell Subtype Surface Markers Derived From Intracellular Proteins.
Not available
S-EPMC6021197 | biostudies-literature
UnknownGeneration of CD8+ T cell-mediated immunity against idiotype-negative lymphoma escapees.
Not available
S-EPMC2777127 | biostudies-literature
UnknownRelationship Between Bone Mineral Density T-Score and Nonvertebral Fracture Risk Over 10 Years of Denosumab Treatment.
Not available
S-EPMC6852155 | biostudies-literature
UnknownA CpG-loaded tumor cell vaccine induces antitumor CD4+ T cells that are effective in adoptive therapy for large and established tumors.
Not available
S-EPMC3037739 | biostudies-literature
UnknownDevelopment of an in situ CAR-T cell protocol through optical and PSMA-targeted PET imaging.
Not available
S-EPMC12184651 | biostudies-literature
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