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ProteomicsColon cancer stem cell over-expressing TAp63α
p63, a member of p53 family, is transcribed in different variants, containing (TA) or lacking (N) the N-terminal transactivation domain. Although the proteins of p53 family share high sequence and structural similarities, distinct functions for p63 are emerging. Here we provided a quantitative prote...
ORGANISM(S): Homo sapiens (Human) 
2014-03-17 | PXD000768 | Pride
Lc-msms Stable isotope dimethyl labeling Colon cancer stem cells P63 
ProteomicsColon cancer stem cell over-expressing ΔNp63α
p63, a member of p53 family, is transcribed in different variants, containing (TA) or lacking (ΔN) the N-terminal transactivation domain. Although the proteins of p53 family share high sequence and structural similarities, distinct functions for p63 are emerging. Here we provided a quantitative prot...
ORGANISM(S): Homo sapiens (Human) 
2014-03-17 | PXD000769 | Pride
Lc-msms Stable isotope dimethyl labeling Colon cancer stem cells P63 
TranscriptomicsLamin A/C is required for SHSY5Y neuroblastoma cell differentiation and its expression is linked to a less malignant phenotype.
The main scientific objective of the project was to investigate whether Lamin A/C could be involved in neuroblastoma differentiation. Moreover, taking into account the significance of differentiation stage in the neuroblastoma tumor progression we have also studied a possible role of Lamin A/C in th...
ORGANISM(S): Homo sapiens 
2013-07-11 | E-GEOD-30677 | biostudies-arrayexpress
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