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UnknownQuality Evaluation of Traditional Chinese Medicine Prescription in Naolingsu Capsule Based on Combinative Method of Fingerprint, Quantitative Determination, and Chemometrics.
Not available
S-EPMC9424029 | biostudies-literature
ProteomicsHeLa cells were transfected with MARVELD1, then treated with or without HU treatment,following with IP and LC-MSMS analysis
To analyze MARVELD1 interacting proteins, HeLa cells were transfected with MARVELD1-Flag or pcDNA3.1 (PC), then treated with 8 mM Hydroxyurea (MCE, USA) or DMSO for 24 h, and subjected to IP assays with anti-DYKDDDDK magnetic agarose (Thermo, USA). After washing five times with PBS buffer, samples w...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD034445 | Pride
Hela cells lc-msms marveld1 hu 
ProteomicsHuman bladder cancer LC MS/MS - A Comprehensive Investigation toward the Indicative Proteins of Bladder Cancer in Urine: From Surveying Cell Secretomes to Verifying Urine Proteins
Urine is an ideal material to study and examine the bladder cancer (BCa) biomarkers, whereas exploration to the corresponding protein candidates is confronting technique challenges. Herein, we proposed a comprehensive strategy of searching the urine proteins related to BCa. The strategy consists of ...
ORGANISM(S): Homo sapiens (Human) 
2016-06-17 | PXD003557 | Pride
Lc ms/ms Bladder cancer Human 
ProteomicsTargeting Pim2 Improves Effector Function and Longevity of CD8 T cells in Cancer Immunotherapy
The Pim kinase family is critically involved in tumorigenesis, yet its function in primary T cells remains poorly understood. We previously reported that Pim2 negatively regulates T-cell responses to alloantigen. To investigate how Pim2 impacts anti-tumor immunity of CD8 T cells, we generated Pim2-/...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-08 | PXD059837 | Pride
Pim2 T cells Cancer Immunotherapy 
ProteomicsURI alleviates tyrosine kinase inhibitors-induced ferroptosis by reprogramming lipid metabolism in p53 wild-type liver cancers. HEK293T cells were transfected with His-URI plasmid before anti-His immunoprecipitation and gel cutting. LC-MS/MS was performed to identify URI potential binding proteins.
URI keeps low levels of p53 in a TRIM28-MDM2 dependent manner, maintains SCD1 activity and accumulation of MUFAs, and subsequently promotes resistance to TKIs in cancer cell. URI-p53-SCD1 axis mediates resistance of TKIs and may explain why p53-wild type HCC still showed intrinsic resistance to TKIs...
ORGANISM(S): Homo sapiens (Human) 
2023-09-15 | PXD045407 | Pride
Uri 
ProteomicsMass spec analysis of the sequences of proteins snFPITE-n1 and snFPITE-n2 from Sipunculus nudus
In this project, we purified proteins snFPITE-n1 and snFPITE-n2 from Sipunculus nudus, digested the proteins and determined the sequences of the proteins by Mass spec analysis. We have a database of the sequences of snFPITE proteins from Sipunculus nudus and we used the Mass spec results to search f...
ORGANISM(S): Sipunculus nudus 
2025-04-03 | PXD043675 | Pride
Sipunculus nudus Mass spec 
UnknownGenetic drivers of heterogeneity in type 2 diabetes pathophysiology.
Not available
S-EPMC10937372 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
UnknownWorldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants.
Not available
S-EPMC8446938 | biostudies-literature
UnknownHeterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight.
Not available
S-EPMC7943191 | biostudies-literature
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