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TranscriptomicsMicroarray analysis of Merkel cell carcinoma (MCC) tumors, small cell lung cancer (SCLC) tumors, and MCC cell lines
When using cell lines to study cancer, phenotypic similarity to the original tumor is paramount. Yet, little has been done to characterize how closely Merkel cell carcinoma (MCC) cell lines model native tumors. To determine their similarity to MCC tumor samples, we characterized MCC cell lines via g...
ORGANISM(S): Homo sapiens 
2014-12-23 | E-GEOD-50451 | biostudies-arrayexpress
GenomicsTargets of Ty3 transposition in Saccharomyces cerevisiae
The goal of these experiments was to define the targets of Ty3 transposition in Saccharomyces cerevisiae. Ty3 is a retroviruslike element that is found at the transcription initiation site of chromosomal tRNA genes. A Ty3 that can be induced by growth in galactose-containing medium and which was ma...
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-02 | E-GEOD-31820 | biostudies-arrayexpress
TranscriptomicsMicroarray comparison of transcriptomic differences between long-term practitioners of the Transcendental Meditation (TM) technique and group-matched non-practitioner controls
Research on the Transcendental Meditation (TM) technique suggests it is a powerful intervention for reducing the unwanted effects of stress. Investigations of the TM program as a therapeutic intervention include cardiovascular disease (CVD), post-traumatic stress disorder (PTSD), and anxiety disorde...
ORGANISM(S): Homo sapiens 
2021-03-26 | E-MTAB-10252 | biostudies-arrayexpress
UnknownParenteral hydration in patients with advanced cancer: a multicenter, double-blind, placebo-controlled randomized trial.
Not available
S-EPMC3530688 | biostudies-literature
UnknownGenotype-guided tamoxifen dosing increases active metabolite exposure in women with reduced CYP2D6 metabolism: a multicenter study.
Not available
S-EPMC3158597 | biostudies-literature
UnknownRandomized phase II study of carboplatin and paclitaxel with either linifanib or placebo for advanced nonsquamous non-small-cell lung cancer.
Not available
S-EPMC5478045 | biostudies-literature
UnknownSPARKLE: a new spark in treating oligorecurrent prostate cancer: adding systemic treatment to stereotactic body radiotherapy or metastasectomy: key to long-lasting event-free survival?
Not available
S-EPMC9743623 | biostudies-literature
TranscriptomicsTetracycline-treated Litomosoides sigmodontis vs. untreated control Litomosoides sigmodontis
The filarial nematodes Brugia malayi, Wuchereria bancrofti and Onchocerca volvulus cause elephantiasis, dermatitis and blindness, resulting in severe morbidity in developing countries. 1.3 billion people are at risk of infection. Targeting the essential Wolbachia endobacteria of filarial nematodes w...
ORGANISM(S): Litomosoides sigmodontis 
2010-04-07 | E-GEOD-20976 | biostudies-arrayexpress
TranscriptomicsA Phase Two Randomised Controlled Trial of Belimumab in Kidney Transplant Recipients Demonstrates Comparable Safety, a Reduction in De Novo Antibody Production and an Increase in Regulatory B Cells.
There is an urgent unmet need in solid organ transplantation for immunotherapeutic strategies that target B cells and plasma cells, ideally without increasing infectious complications. We conducted a phase 2 double-blind randomised placebo-controlled trial to assess the safety and potential efficacy...
ORGANISM(S): Homo sapiens 
2018-06-11 | E-MTAB-5906 | biostudies-arrayexpress
TranscriptomicsExpression data from A2780 (cisplatin-sensitive) and Round5 A2780 (cisplatin-resistant) cell lines.
Cisplatin and carboplatin are the primary first-line therapies for the treatment of ovarian cancer. However, resistance to these platinum-based drugs occurs in the large majority of initially responsive tumors, subsequently resulting in a poor long-term prognosis. To model the onset of drug resista...
ORGANISM(S): Homo sapiens 
2009-04-17 | E-GEOD-15372 | biostudies-arrayexpress
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