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Protein tyrosine phosphorylation (pTyr) is controlled by protein tyrosine kinases and phosphatases (PTPs) and allows cells to sense and respond to changes in their environment. Pervanadate is a widely used chemical tool that induces global pTyr, a phenomenon attributed to its properties as a PTP inh...
ORGANISM(S): Homo sapiens (Human) 
2026-03-10 | PXD059641 | Pride
Protein tyrosine sulfation (sY) is a post-translational modification (PTM) catalysed by Golgi-resident Tyrosyl Protein Sul-foTransferases (TPSTs). Information on protein tyrosine sulfation is currently limited to ~50 human proteins with only a handful of those having verified sites of sulfation. The...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD043723 | Pride

The ARRA Autism Sequencing Collaboration was created in 2010 bringing together expert large-scale sequencing center (at the Baylor College of Medicine, PI Richard Gibbs and the Board Institute of MIT and Harvard, PI Mark J. Daly) and a collaborative network of research labs focused on the genetic...

One of our new major finding among the genes that contributes to MS susceptibility is ICSBP1. The so called disease modifying therapies like interferon-beta (IFN-β), possibly acting on the peripheral T-cells, reduce the disease activity and the clinical progression, with a MRI-detectable effect in ...
ORGANISM(S): Homo sapiens 
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