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ProteomicsComprehensive investigation of (redox-) proteomic changes induced by cana-, dapa-, empagliflozin treatment in cardiac cells
One of the major macrovascular complications that can occur in type 2 diabetes is the development of cardiovascular diseases as for instance heart failure. However, sodium-glucose co-transporter-2 (SGLT-2) inhibitors have shortly after their approval shown to decrease death rates in diabetic patient...
ORGANISM(S): Homo sapiens (Human) 
2026-01-20 | PXD063467 | Pride
Gliflozins Sglt-2 inhibitors Proteomics Ac16 cells Heart failure Oxidative stress Hcm cells Empagliflozin Redox proteomics Canagliflozin Dapagliflozin 
UnknownEffect of dapagliflozin on anaemia in DAPA-HF.
Not available
S-EPMC11497230 | biostudies-literature
GenomicsBoth TRULI and DAPA may serve as anti-OA drugs by modulating ZBTB20 to restore ECM homeostasis
Both TRULI and DAPA may serve as anti-OA drugs by modulating ZBTB20 to restore ECM homeostasis
PRJNA1123580 | ENA
ProteomicsRole of the DapA protein in iron homeostasis and the metabolism of cyanide in jewelery wastewaters
Quantitative free labeling proteomics to elucidate the role of the DapA protein in iron metabolism and the assimilation of cyanide in the bacterium Pseudomonas pseudoalcaligenes. Integration, validation and discussion of results using other non-proteomic techniques such as qRT-PCR and determination ...
ORGANISM(S): Pseudomonas pseudoalcaligenes CECT 5344 Bacteria 
2020-02-18 | PXD014027 | Pride
Pseudomonas pseudoalcaligenes cect5344 Cyanide metabolism Proteomics Iron homeostasis Dapa 
UnknownIron Deficiency in Heart Failure and Effect of Dapagliflozin: Findings From DAPA-HF.
Not available
S-EPMC9508991 | biostudies-literature
GenomicsRED_study
Effect of DAPA en GLIC on fecal microbiome
PRJEB35175 | ENA
TranscriptomicsBoth TRULI and DAPA may serve as anti-OA drugs by modulating ZBTB20 to restore ECM homeostasis
Due to the existing challenges in modulating the activity of transcription factors directly, comprehending the upstream regulatory mechanism can offer perspectives for tackling these obstacles. Our observations that in early-stage OA chondrocytes ZBTB20 translocates into nucleus in a LATS1-dependent...
ORGANISM(S): Homo sapiens 
2025-03-19 | GSE269735 | GEO
UnknownEffects of Dapagliflozin in Chronic Kidney Disease, With and Without Other Cardiovascular Medications: DAPA-CKD Trial.
Not available
S-EPMC10227210 | biostudies-literature
UnknownSafety and efficacy of dapagliflozin in patients with focal segmental glomerulosclerosis: a prespecified analysis of the dapagliflozin and prevention of adverse outcomes in chronic kidney disease (DAPA-CKD) trial.
Not available
S-EPMC9395378 | biostudies-literature
UnknownExtrapolated longer-term effects of the DAPA-CKD trial: a modelling analysis.
Not available
S-EPMC10157747 | biostudies-literature
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