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UnknownPersonality traits measured by the HEXACO personality inventory and the dark triad predict university students' attitudes and misconduct behaviors related to generative artificial intelligence : Haiying Liang<sup>1</sup>, Xu Mao<sup>2</sup>, Michael J. Reiss<sup>3</sup>.
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S-EPMC12647770 | biostudies-literature
TranscriptomicsInhibition of the mitochondrial TCA cycle by monofluoroacetate in Arabidopsis thaliana
Plant mitochondria signal to the nucleus leading to altered transcription of nuclear genes by a process called mitochondrial retrograde regulation (MRR). MRR is implicated in metabolic homeostasis and responses to stress conditions. Transcriptional consequences on nuclear gene expression of mitochon...
ORGANISM(S): Arabidopsis thaliana 
2013-01-01 | E-GEOD-29268 | biostudies-arrayexpress
TranscriptomicsInhibition of the mitochondrial electron transport chain by antimycin A in Arabidopsis thaliana
Plant mitochondria signal to the nucleus leading to altered transcription of nuclear genes by a process called mitochondrial retrograde regulation (MRR). MRR is implicated in metabolic homeostasis and responses to stress conditions. Transcriptional consequences on nuclear gene expression of mitochon...
ORGANISM(S): Arabidopsis thaliana 
2013-01-01 | E-GEOD-29204 | biostudies-arrayexpress
MetabolomicsHuman Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice
Autism spectrum disorder (ASD) manifests as alterations in complex human behaviors including social communication and stereotypies. In addition to genetic risks, the gut microbiome differs between typically-developing (TD) and ASD individuals, though it remains unclear whether the microbiome contrib...
2019-07-04 | MTBLS726 | MetaboLights
ProteomicsCircadian Rhythms in Cyanobacterial Protein Condensation
Circadian rhythms are endogenously generated daily cycles in physiology that are closely tied to metabolism and can be found in all kingdoms of life. In cyanobacteria, energy storage through glycogen metabolism is highly rhythmic, but the underlying mechanisms remain unclear. Here we find that the g...
ORGANISM(S): Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2) Bacteria 
2026-05-25 | PXD074299 | Pride
Circadian Cyanobacteria 
ProteomicsEtomoxir: A Promiscuous Fatty Acid Mimetic Chemoproteomic Probe
Etomoxir has been used for decades as a popular small molecule inhibitor of Carnitine Palmitoyltransferase I, Cpt1, to block mitochondrial fatty acid b-oxidation. To test the specificity of etomoxir, we generated click chemistry enabled reagents to label etomoxir binding proteins in situ. Etomoxir b...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-04 | PXD051969 | Pride
Liver Fatty acid oxidation Cpt1 Etomoxir 
ProteomicsEtomoxir as a Promiscuous Chemoproteomic Probe.
Primary hepatocytes from WT or Pex5KO mouse livers were treated with 100uM clickable etomoxir analogues and the proteins bound to etomoxir were pulled down and identified. The small molecule inhibitor etomoxir has been used for many years as a specific inhibitor of Cpt1 but these data show that etom...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD045866 | Pride
Liver Fatty acid oxidation Cpt1 Etomoxir 
TranscriptomicsSystems Toxicology Identifies Mechanistic Impacts of 2-amino-4,6-dinitrotoluene (2-ADNT) Exposure in Northern Bobwhite
A systems toxicology investigation comparing and integrating transcriptomic and proteomic results was conducted to pursue a holistic understanding of the effects of the explosives degradation product 2-amino-4,6-dinitrotoluene (2A-DNT) dosing on the health of the wildlife bird model, Northern bobwhi...
ORGANISM(S): Colinus virginianus 
2015-07-01 | E-GEOD-59910 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of Emiliania huxleyi infected with coccolithovirus to investigate EhV-99B1 strain diversity
Following on from a pilot study to investigate the diversity of the coccolithoviruses, a second small scale microarray experiment was performed in order to provide genomic content information to aid the sequencing of a third coccolithovirus genome, EhV-99B1.
ORGANISM(S): Emiliania huxleyi 
2007-12-17 | E-MAXD-23 | biostudies-arrayexpress
ProteomicsRab30 regulates lipid homeostasis in the hepatocyte during fasting
In order to facilitate inter-tissue communication and exchange of proteins, lipoproteins, and metabolites with the circulation, hepatocytes have an intricate and efficient intracellular trafficking system regulated by small Rab GTPases. Rab30, a putative Golgi-localized Rab GTPase, is induced in th...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-04 | PXD050376 | Pride
Rab gtpases  liver  ppara  lipid metabolism  fasting 
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