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Proof of principle and testing experiments on  iPS2-sci-seq have been performed on two batches of hPSC-derived cardiomyocytes at day 23. Cells have been treated with Tetracycline throughout differentiation. For this experiment it was used a 2-level of indexing sci-RNAseq protocol (Cao J. et. al, Sci...
ORGANISM(S): Homo sapiens 
High resolution mass spectrometry-based proteomics generates large amounts of data, even in the standard liquid chromatography (LC) – tandem mass spectrometry configuration. Adding an ion mobility dimension vastly increases the acquired data volume, challenging both analytical processing pipe...
ORGANISM(S): Homo sapiens (Human) 
2021-07-30 | PXD027359 | Pride
Open modification searching (OMS) is a powerful search strategy that identifies peptides carrying any type of modification by allowing a modified spectrum to match against its unmodified variant by using a very wide precursor mass window. A drawback of this strategy, however, is that it leads to a l...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2021-05-25 | PXD009861 | Pride

To better understand the effect of different LC-MS setups on metabolite detection, five laboratories analyzed 1298 standard compounds obtained from the MetaSci metabolite standard library, classified as 'Human Endosome' (HE), 'Food Exposome' (FE), 'Chemical Exposome' (CE), 'Microbiota Exposome' (...

2026-04-24 | MTBLS14343 | MetaboLights
High-content single-cell combinatorial indexing
Profiling single-cell histone modifications using indexing chromatin immunocleavage sequencing
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