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TranscriptomicsTranscriptional profiling by array of yeast to identify genes inhibiting mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia
Haplo-insufficiency profiling followed by Gene-set enrichment analysis of sensitive strains was conducted in yeast treated with tigecycline. This revealed significant enrichment of genes involved in mitochondrial translation, similar to that seen with the known mitochondrial translation inhibitors ...
ORGANISM(S): Saccharomyces cerevisiae 
2011-11-01 | E-MTAB-814 | biostudies-arrayexpress
TranscriptomicsIdentification of drugs that enhance skin repair using dermal stem cell-based screens [Rat]
Here, we asked whether we could identify pharmacological agents that enhance endogenous stem cell function to promote skin repair, focusing on SKPs (skin-derived precursors) a dermal precursor cell population. Libraries of compounds already used in humans were screened for their ability to enhance t...
ORGANISM(S): Rattus norvegicus 
2015-12-24 | E-GEOD-73328 | biostudies-arrayexpress
UnknownHypophosphorylated pRb knock-in mice exhibit hallmarks of aging and vitamin C-preventable diabetes
Not available
S-SCDT-EMBOJ-2020-106825P | biostudies-other
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