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ProteomicsAn azidoribose probe to track ketoamine adducts in histone ribose glycation (293T nuclei - LFQ)
Reactive cellular metabolites can modify macromolecules and form adducts known as non-enzymatic covalent modifications (NECMs). Dissecting the mechanisms, regulation and consequences of NECMs, such as glycation, has been challenging due to the complex and often ambiguous nature of the adducts formed...
ORGANISM(S): Homo sapiens (Human) 
2020-05-15 | PXD019204 | Pride
Glycation Proteomics Ribose Epigenetics Histones Click chemistry 
TranscriptomicsSmoking-induced Disarray of the Apical Junctional Complex Gene Expression Architecture in the Human Airway Epithelium
The apical junctional complex (AJC), composed of tight junctions and adherens junctions, is essential for maintaining epithelial barrier function. Since cigarette smoking and chronic obstructive pulmonary disease (COPD), the major smoking-induced disease, are both associated with increased lung epit...
ORGANISM(S): Homo sapiens 
2011-06-27 | E-GEOD-20257 | biostudies-arrayexpress
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