Sort   by:  
 Page size 
MetabolomicsA Metabolomic Approach for Predicting Diurnal Changes in Cortisol

INTRODUCTION: The dysregulation of cortisol secretion has been associated with a number of mental health and mood disorders. However, diagnostics for mental health and mood disorders are behavioral and lack biological contexts.

OBJECTIVES: The goal of this ...

2021-09-23 | MTBLS1206 | MetaboLights
TranscriptomicsTranscription profiling by array of mouse embryonic stem cell lines with Dgcr8 mutations to investigate the broad role of miRNAs and individual miRNAs through the reintroduction of miRNA mimics
These experiments were conducted as part of a study to derive the targets of miRNAs. Two independent BayGenomics mouse embryonic stem cell lines (XH157 and XG058), each bearing a gene trap between exons 9 and 10 of the Dgcr8 locus (ENSMUST00000115633, Ensembl v53) were further mutagenised by the tar...
ORGANISM(S): Mus musculus 
2012-08-20 | E-MTAB-418 | biostudies-arrayexpress
TranscriptomicsA multiplexed assay to identify condition-dependent changes in protein-protein interactions
Testing the effect of 80 small molecules on the interaction between 250 protein pairs
ORGANISM(S): Saccharomyces cerevisiae 
2012-04-02 | E-MEXP-3467 | biostudies-arrayexpress
TranscriptomicsEffects of ONC201 on mantle cell lymphoma cell lines
The small molecule ONC201 is toxic in vitro to multiple cell lines and primary tumor samples of mantle cell lymphoma (MCL) and acute myeloid leukemia, even ones with unfavorable genetic features (notably including TP53 inactivation) or acquired resistance to other agents. Because the mechanism of ac...
ORGANISM(S): Homo sapiens 
2016-02-20 | E-GEOD-68091 | biostudies-arrayexpress
TranscriptomicsmiR-25 regulates Wwp2 and Fbxw7 and promotes reprogramming of mouse somatic cells
To reprogram mouse embryonic fibroblasts (MEFs) to induced Pluripotent Stem Cells (iPSCs), we constructed the PiggyBac (PB) transposon carrying the four Yamanaka factor cDNAs controlled by a CAG promoter (PB-CAG-OCKS, Oct4, cMyc, Klf4 and Sox2). As the baseline reprogramming control, we transfected ...
ORGANISM(S): Mus musculus 
2011-10-10 | E-MTAB-409 | biostudies-arrayexpress
TranscriptomicsmiRNA expression in C. elegans fem-2(b245ts) and fem-3(q20ts) mutants
We compared animals that produce oocytes but no sperm fem-2(b245ts) to animals that produce sperm but no oocytes fem-3(q20ts). Using miRNA microarrays and we found that the mir-35-41 cluster genes were expressed to much greater extent in oogenesis than in spermatogenesis; furthermore, these miRNAs w...
ORGANISM(S): Caenorhabditis elegans 
2010-05-16 | E-GEOD-19557 | biostudies-arrayexpress
UnknownDesign and Baseline Characteristics of the Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease Trial.
Not available
S-EPMC6888890 | biostudies-literature
UnknownUsing CSF biomarkers to replicate genetic associations in Alzheimer's disease.
Not available
S-EPMC3150628 | biostudies-literature
UnknownPlasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema.
Not available
S-EPMC6568257 | biostudies-literature
UnknownSocializing One Health: an innovative strategy to investigate social and behavioral risks of emerging viral threats.
Not available
S-EPMC8122533 | biostudies-literature
Sort   by:  
 Page size