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UnknownInduction of potent NK cell-dependent anti-myeloma cytotoxic T cells in response to combined mapatumumab and bortezomib.
Not available
S-EPMC4570118 | biostudies-literature
TranscriptomicsSpt6 regulates intragenic and antisense transcription, nucleosome positioning, and histone modifications genome-wide in fission yeast [RNA-seq]
Spt6 is a highly conserved histone chaperone that interacts directly with both RNA polymerase II and histones to regulate gene expression. To gain a comprehensive understanding of the requirements for this critical factor, we have performed genome-wide analyses of transcription, chromatin structure...
ORGANISM(S): Schizosaccharomyces pombe 
2013-10-09 | E-GEOD-49573 | biostudies-arrayexpress
ProteomicsA genetically-encoded crosslinker screen identifies SERBP1 as a PKC substrate influencing translation and cell division
The PKC-regulated genome protective pathway provides transformed cells a failsafe to successfully complete mitosis. Despite the necessary role for Aurora B in this programme, it is unclear whether its requirement is sufficient or if other PKC cell cycle targets are involved. To address this, we deve...
ORGANISM(S): Homo sapiens (Human) 
2021-12-09 | PXD029091 | Pride
Human 
UnknownCirculating tumor cell counts are prognostic of overall survival in SWOG S0421: a phase III trial of docetaxel with or without atrasentan for metastatic castration-resistant prostate cancer.
Not available
S-EPMC3970171 | biostudies-literature
GenomicsSpt6 regulates intragenic and antisense transcription, nucleosome positioning, and histone modifications genome-wide in fission yeast [Mnase-seq]
Spt6 is a highly conserved histone chaperone that interacts directly with both RNA polymerase II and histones to regulate gene expression. To gain a comprehensive understanding of the requirements for this critical factor, we have performed genome-wide analyses of transcription, chromatin structure...
ORGANISM(S): Schizosaccharomyces pombe 
2013-10-09 | E-GEOD-49572 | biostudies-arrayexpress
GenomicsSpt6 regulates intragenic and antisense transcription, nucleosome positioning, and histone modifications genome-wide in fission yeast
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Schizosaccharomyces pombe 
2013-10-09 | E-GEOD-49575 | biostudies-arrayexpress
ProteomicsCoordinated control of the Aurora B abscission checkpoint by PKCε complex assembly, midbody recruitment and retention
The N371 site on PKCe was mutated to TAG in an expression plasmid. This was co-transfected in a 1:1 ratio with a plasmid that encodes both an aaRS optimised to recognise AbK, and the tRNAPyl which recognises the UAG codon.
ORGANISM(S): Mus musculus (Mouse) 
2021-11-03 | PXD025959 | Pride
14-3-3 pkce Mass spectrometry Phosphorylation 
ProteomicsPLK1 inhibition induces synthetic lethality in Fanconi anemia pathway-deficient acute myeloid leukemia
Overall survival of acute myeloid leukemia (AML) remains limited. Inhibitors of the master mitotic kinase PLK1 have emerged as promising therapeutics, demonstrating efficacy in an undefined subset of AML patients. However, the clinical success of PLK1 inhibitors remains hindered by a lack of predict...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-12-09 | MSV000096625 | MassIVE
UnknownThe VAMPIRE challenge: A multi-institutional validation study of CT ventilation imaging.
Not available
S-EPMC6605778 | biostudies-literature
UnknownA genome-wide association study identifies susceptibility loci for nonsyndromic sagittal craniosynostosis near BMP2 and within BBS9.
Not available
S-EPMC3736322 | biostudies-literature
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