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TranscriptomicsThe impact of breed genotype and tissue compartment on the response of pig macrophages to lipopolysaccharide
The domestic pig (Sus scrofa) provides a large animal model for human innate immune responses and inflammation that is also economically important in its own right. Results: We demonstrate that macrophages can be harvested from 3 different compartments of the pig (lungs, blood and bone-marrow), cryo...
ORGANISM(S): Sus scrofa 
2013-04-13 | E-GEOD-45145 | biostudies-arrayexpress
ProteomicsMenstrual fluid-derived extracellular vesicles as a non-invasive diagnostic tool for endometriosis
Introduction: Endometriosis is a debilitating condition where endometrial-like tissue grows outside the uterus and rarely in distant sites such as the lungs, heart and brain. Symptoms are severe chronic pain, bladder/bowel problems, painful sex and infertility. Differences in endometrium between wom...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD042101 | Pride
Endometriosis Extracellular vesicles Non-invasive diagnosis Menstrual fluid 
TranscriptomicsKey hub and bottleneck genes differentiate the macrophage response to virulent and attenuated Mycobacterium bovis
Mycobacterium bovis is an intracellular pathogen that causes tuberculosis in cattle. Following infection, the pathogen resides and persists inside host macrophages by subverting host immune responses via a diverse range of mechanisms. Here, a high-density bovine microarray platform was used to exami...
ORGANISM(S): Bos taurus 
2014-08-01 | E-GEOD-59774 | biostudies-arrayexpress
TranscriptomicsA Gene Expression Atlas of the Domestic Pig
A Gene Expression Atlas of the Domestic Pig
ORGANISM(S): Sus scrofa 
2012-09-01 | E-MTAB-1183 | biostudies-arrayexpress
UnknownCNX-012-570, a direct AMPK activator provides strong glycemic and lipid control along with significant reduction in body weight; studies from both diet-induced obese mice and db/db mice models.
Not available
S-EPMC3906767 | biostudies-literature
TranscriptomicsTAL1 knock down in human erythroid progenitors
We used microarray profiling in erythroid cells to uncover TAL1 dependent genes in a hematopoietic differentiation context. Differentiated ex vivo hematopoietic multipotential progenitors isolated from adult peripheral blood. The knockdown of TAL1 (KD) was induced in pro-erythroblasts (Days 8 and 9 ...
ORGANISM(S): Homo sapiens 
2010-12-14 | E-GEOD-20545 | biostudies-arrayexpress
no omics definedTranscription profiling of two highly salt-tolerant wheat lines, their parental lines, and a salt-sensitive line in salt stress and control growth conditions
Comparative expression analysis between two highly salt-tolerant wheat lines, their parental lines, and a salt-sensitive line. The Chinese Spring (CS) line is salt sensitive. AJDAj5 and PhI are the two parental lines (with Chinese Spring background), and both have some salt-tolerance. W4909 and W491...
ORGANISM(S): Triticum aestivum 
2007-07-26 | E-MEXP-971 | biostudies-arrayexpress
TranscriptomicsMNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL
The phosphorylation of eIF4E1 at serine 209 by MNK1 or MNK2 has been shown to initiate oncogenic mRNA translation, a process that favours cancer development and maintenance. Here, we interrogate the MNK-eIF4E axis in diffuse large B-cell lymphoma (DLBCL) and show a distinct distribution of MNK1 and ...
ORGANISM(S): Homo sapiens 
2014-11-18 | E-GEOD-61691 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression of bovine monocyte-derived macrophages in response to in vitro challenge with Mycobacterium bovis
Background: Mycobacterium bovis, the causative agent of bovine tuberculosis, is a major cause of mortality in global cattle populations. Macrophages are among the first cells types to encounter M. bovis following exposure and the response elicited by these cells is pivotal in determining the outcome...
ORGANISM(S): Bos taurus 
2011-12-31 | E-GEOD-33309 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human and Arabidopsis cells to develop a pipeline for data processing of Agilent oligonucleotide expression arrays
From analysis of error and reproducibility to a pipeline for data processing of Agilent oligonucleotide expression arrays.
ORGANISM(S): Arabidopsis thaliana 
2010-09-07 | E-TABM-942 | biostudies-arrayexpress
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