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UnknownSubmaximal 2-day cardiopulmonary exercise testing to assess exercise capacity and post-exertional symptom exacerbation in people with long COVID.
Not available
S-EPMC12857497 | biostudies-literature
MetabolomicsEx-Vivo Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study
Osteoarthritis (OA) is an age-related degenerative musculoskeletal disease characterised by loss of articular cartilage, synovitis, abnormal bone proliferation and subchondral bone sclerosis. Underlying OA pathogenesis is yet to be fully elucidated with no OA specific biomarkers in clinical use. Ex-...
2020-09-30 | MTBLS1495 | MetaboLights
MetabolomicsA Metabolomic Approach for Predicting Diurnal Changes in Cortisol

INTRODUCTION: The dysregulation of cortisol secretion has been associated with a number of mental health and mood disorders. However, diagnostics for mental health and mood disorders are behavioral and lack biological contexts.

OBJECTIVES: The goal of this ...

2021-09-23 | MTBLS1206 | MetaboLights
Unknown561. Safety of Remdesivir vs Standard Care in Patients with Moderate Covid-19
Not available
S-EPMC7777368 | biostudies-literature
UnknownHow Rainfall Variation Influences Reproductive Patterns of African Savanna Ungulates in an Equatorial Region Where Photoperiod Variation Is Absent.
Not available
S-EPMC4546645 | biostudies-literature
TranscriptomicsTranscription profiling of F344/N rats administered with potassium bromate in the drinking water
Ozone has been proposed for water disinfection because it is more efficient than chlorine for killing microbes and results in much lower levels of carcinogenic trihalomethanes than does chlorination. Ozone leads to formation of hypobromous acid in surface waters with high bromine content and forms b...
ORGANISM(S): Rattus norvegicus 
2006-11-14 | E-TOXM-21 | biostudies-arrayexpress
TranscriptomicsRNA-seq of rat microglia, mouse neurons and human astrocytes in co-culture, challenged with different concentrations of LPS - dataset 2
We investigated non-cell-autonomous regulation of gene expression in microglia by neurons and astrocytes, by co-culturing these cell types (derived from different mammalian species) together, and then separating the RNA-seq reads from each cell type/species in silico. This submission forms a compani...
ORGANISM(S): mixed sample 
2021-03-23 | E-MTAB-7776 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human and mouse stem-cell derived neurons and mouse primary cortical neurons after KCl-induced membrane depolarization against controls.
This experiment comprises RNA-seq data used to study evolutionary differences between humans and mice in neuronal activity-dependent transcriptional responses. Activity-dependent transcriptional responses in developing human stem cell-derived cortical neurons were compared with those induced in deve...
ORGANISM(S): Mus musculus 
2017-02-16 | E-MTAB-5489 | biostudies-arrayexpress
TranscriptomicsRNA-seq of mouse astrocytes in monoculture and co-cultured with rat neurons (both inactive and active).
Neurons induce a dramatic transformation in developing astrocytes, causing them to develop a complex stellate morphology resembling their appearance in vivo. However, the transcriptional changes that accompany this transformation are not known, nor are the signalling mechanisms responsible. Similarl...
ORGANISM(S): Rattus norvegicus 
2017-05-02 | E-MTAB-5514 | biostudies-arrayexpress
UnknownBreast milk pharmacokinetics of efavirenz and breastfed infants' exposure in genetically defined subgroups of mother-infant pairs: an observational study.
Not available
S-EPMC6542686 | biostudies-literature
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