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As pancreatic ductal adenocarcinoma (PDAC) is the deadliest solid cancer, and new immunological therapies have only marginally improved patient survival, we aimed at better understainding the immunological fingerprint of this disease. PDAC development involves inflammatory reprogramming and bacteria...
ORGANISM(S): Homo sapiens 
In order to identify genes specifically involved in the photoperiodic control of the mobilisation programme for starch reserve in Arabidopsis thaliana transcription profiling was performed on the following genotypes Columbia wild type (Col-0), CO overexpressor (35S::CO), CO muntant (co-10), GBSSI mu...
ORGANISM(S): Arabidopsis thaliana 
Concentration- and time- response and human lower EpiAveolar™ respiratory tract tissues comparison of transcriptional responses following 12-day exposure with different test materials. Differential expression and pathway analyses were performed to estimate the lowest transcriptional point of depar...
ORGANISM(S): Homo sapiens 
The apicomplexan parasite Cystoisospora suis has global significance as an enteropathogen of suckling piglets. Its intricate life cycle entails a transition from an asexual phase to sexual development, ultimately leading to the formation of transmissible oocysts. To advance our understanding of the ...
ORGANISM(S): Cystoisospora suis 
2023-10-13 | PXD045050 | Pride

Root mutualistic microbes can modulate the production of plant secondary metabolites affecting plant–herbivore interactions. Still, the main mechanisms underlying the impact of root mutualists on herbivore performance remain ambiguous. In particular, little is known about how changes in the plant...

2023-09-12 | MTBLS2700 | MetaboLights
The experiment was designed in order to knock down the expression of TLX1 gene in T-ALL cell line We used microarrays to identify the gene expression signatures associated with TLX1 knock down in ALLSIL ALLSIL cell lines were infected with pLKO.1-shTLX1 and pLKO.1-luc control lentivirus. After 5 day...
ORGANISM(S): Homo sapiens 
We used Affymetrix microarrays to investigate gene expression changes in PBMNCs isolated from female and male pigs to determine significant modulatory effects that may have been induced by the intake of resveratrol during 9 months in high-fat fed animals . The aim of this work was to determine wheth...
ORGANISM(S): Sus scrofa 
We performed a microarray experiment to assess the global changes in transcription occurring in leaves and roots of the vitamin B6 deficient pdx1.3 knockout mutant in comparison to WT. Vitamin B6 (pyridoxal 5′-phosphate) is an essential cofactor of many metabolic enzymes. Plants biosynthesize the vi...
ORGANISM(S): Arabidopsis thaliana 
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