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ProteomicsGermline encoded residues dominate the interaction of a human monoclonal antibody with Decorin binding protein A (DbpA) of Borrelia burgdorferi
During the course of Lyme disease, humans mount a robust and sustained antibody response against dozens of Borrelia burgdorferi outer surface lipoproteins. Identifying which antibodies are associated with spirochete clearance and disease resolution is of paramount importance in therapeutic developme...
ORGANISM(S): Homo sapiens (Human) 
2025-07-28 | PXD062826 | Pride
Monoclonal Borrelia Dbpa Hdx-ms 
UnknownDbpA is a region-specific RNA helicase.
Not available
S-EPMC5179288 | biostudies-literature
UnknownIdentification of lysine residues in the Borrelia burgdorferi DbpA adhesin required for murine infection.
Not available
S-EPMC4136201 | biostudies-literature
UnknownActive and passive immunity against Borrelia burgdorferi decorin binding protein A (DbpA) protects against infection.
Not available
S-EPMC108175 | biostudies-literature
UnknownThe ATPase cycle mechanism of the DEAD-box rRNA helicase, DbpA.
Not available
S-EPMC2359651 | biostudies-literature
UnknownStructural basis for the activation of the DEAD-box RNA helicase DbpA by the nascent ribosome.
Not available
S-EPMC8536315 | biostudies-literature
UnknownCold Shock Domain Protein DbpA Orchestrates Tubular Cell Damage and Interstitial Fibrosis in Inflammatory Kidney Disease.
Not available
S-EPMC10217384 | biostudies-literature
UnknownA dominant negative mutant of the E. coli RNA helicase DbpA blocks assembly of the 50S ribosomal subunit.
Not available
S-EPMC2770675 | biostudies-literature
UnknownResonance assignment and secondary structure of DbpA protein from the European species, Borrelia afzelii.
Not available
S-EPMC8481140 | biostudies-literature
UnknownStrain-specific variation of the decorin-binding adhesin DbpA influences the tissue tropism of the lyme disease spirochete.
Not available
S-EPMC4117581 | biostudies-literature
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