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This study demonstrates that adding the non-ionic surfactant n-dodecyl-β-D-maltopyranoside (DDM) during protein resolubilization improves the identification of hydrophobic peptides and proteins in bottom-up proteomics. DDM's effectiveness in overcoming the challenge of losing hydrophobic proteins af...
ORGANISM(S): Homo sapiens (Human) 
2025-12-16 | PXD068353 | Pride
This study demonstrates that adding the non-ionic surfactant n-dodecyl-β-D-maltopyranoside (DDM) during protein resolubilization improves the identification of hydrophobic peptides and proteins in bottom-up proteomics. DDM's effectiveness in overcoming the challenge of losing hydrophobic proteins af...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-16 | PXD064279 | Pride
We developed an ultrasensitive top down platform by incorporating a microfluidic sample preparation system, termed nanoPOTS (Nanodroplet Processing in One pot for Trace Samples), into a top down workflow. We determined that a unique combination of a nonionic detergent DDM with urea as a protein extr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-11-22 | MSV000084612 | MassIVE
Identification of flavin containing bands on a gel after on high-resolution Clear Native electrophoresis of DDM-solubilized mouse brain mitochondria
ORGANISM(S): Mus musculus (Mouse) 
2022-02-15 | PXD028113 | Pride
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