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Transcriptomicsarabidopsis_thaliana_floral_meristem_atlas
Transcriptomic changes during early developmental stages of reproductive meristems in Arabidopsis thaliana. Through laser microdissection coupled to RNA sequencing, we provide precise transcriptomic analysis of the inflorescence meristem, floral meristem and of the flower at the beginning of organ d...
ORGANISM(S): Arabidopsis thaliana 
2014-10-02 | E-MTAB-1946 | biostudies-arrayexpress
TranscriptomicsmicroRNA and cancer progression in breast tumors
miRNAs are small non-coding RNAs frequently altered in human malignancies. They regulate protein-coding gene expression by mediating mRNA degradation and/or repressing translation via the association with the 3M-bM-^@M-^Y untranslated region (3M-bM-^@M-^Y UTR) of the mRNAs. Aberrant miRNA expression...
ORGANISM(S): Homo sapiens 
2012-12-16 | E-GEOD-26659 | biostudies-arrayexpress
TranscriptomicsmiR148b is a major coordinator of breast cancer progression in a relapse-associated microRNA signature by targeting ITGA5, ROCK1, PIK3CA, NRAS and CSF1
Breast cancer is often fatal during its metastatic dissemination. To unravel the role of microRNAs (miRs) during malignancy, we analyzed miR expression in 77 primary breast carcinomas and identified 16 relapse-associated miRs that correlate with survival and/or distinguish tumor subtypes in differen...
ORGANISM(S): Homo sapiens 
2012-12-16 | E-GEOD-26666 | biostudies-arrayexpress
TranscriptomicsExpression quantitative trait loci (eQTL) analysis of mouse lung tumors
To detect genetic variations affecting gene expression in mouse lung tumor tissue, we carried out a genetic linkage study on the transcriptome of lung tumors induced by urethane in an (A/J x C57BL/6)F4 intercross population, whose individual lung tumor multiplicity (Nlung) is linked to the genotype ...
ORGANISM(S): Mus musculus 
2016-03-14 | E-GEOD-71232 | biostudies-arrayexpress
GenomicsGenomic and Proteomic Analyses of Prdm5 Reveal Interactions with Insulator Binding Proteins in Embryonic Stem Cells (ChIP-seq)
PRDM proteins belong to the SET domain protein family, which is involved in the regulation of gene expression. Although few PRDM members possess histone methyltransferase activity, the molecular mechanisms by which the other members exert transcriptional regulation remain to be delineated. In this s...
ORGANISM(S): Mus musculus 
2013-10-31 | E-GEOD-51816 | biostudies-arrayexpress
UnknownRenal primordia activate kidney regenerative events in a rat model of progressive renal disease.
Not available
S-EPMC4374877 | biostudies-literature
TranscriptomicsSphingobium Nickel resistance analysis by RNA-seq approach
Nickel is an essential component of many eukaryotic and prokaryotic metallo-enzymes. Due to its employment in many industrial applications, wastewaters from industrial plants often contain millimolar concentrations of Ni2+ that are toxic and life-threatening for many organism. Several lines of pre...
ORGANISM(S): Sphingobium sp. ba1 
2017-07-03 | E-MTAB-5828 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of miR27a over-expressing RH36 cell lines.
In order to identify direct or indirect miR-27a modulated genes, RH36 cells transfected with miR-27a precursors (pre-miR-27a or pre-control), analyzed 48h post-transfection, were used to perform microarray analysis. Gene expression profiling was carried out in ERMS cell line (RH36) transfected with...
ORGANISM(S): Homo sapiens 
2015-05-04 | E-GEOD-52678 | biostudies-arrayexpress
TranscriptomicsGenomic and Proteomic Analyses of Prdm5 Reveal Interactions with Insulator Binding Proteins in Embryonic Stem Cells (RNA-seq)
PRDM proteins belong to the SET domain protein family, which is involved in the regulation of gene expression. Although few PRDM members possess histone methyltransferase activity, the molecular mechanisms by which the other members exert transcriptional regulation remain to be delineated. In this s...
ORGANISM(S): Mus musculus 
2013-10-31 | E-GEOD-51553 | biostudies-arrayexpress
TranscriptomicsTranscriptome of non-involved lung parenchyma from smoker lung adenocarcinoma patients from Milan, Italy.
Scientific evidence indicates that genetic factors may contribute to differences in lung cancer risk for individuals with similar levels of tobacco exposure, which is the main environmental risk factor of lung cancer. Moreover, lung cancer patients show large differences in clinical staging and surv...
ORGANISM(S): Homo sapiens 
2016-01-20 | E-GEOD-71181 | biostudies-arrayexpress
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