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MetabolomicsUntargeted LC-MS metabolomic studies of Asteraceae species to discover inhibitors of Leishmania major dihydroorotate dehydrogenase

INTRODUCTION: Interesting data about the family Asteraceae as a new source of Leishmania major dihydroorotate dehydrogenase (LmDHODH) inhibitors are presented. This key macromolecular target for parasites causing neglected diseases catalyzes the fourth reaction of the de novo pyr...

2019-10-14 | MTBLS722 | MetaboLights
ProteomicsSexual crossing of thermophilic fungus Myceliophthora heterothallica improved enzymatic degradation of sugar beet pulp
Enzymatic degradation of plant biomass requires a complex mixture of many different enzymes. Like most fungi, thermophilic Myceliophthora species therefore have a large set of enzymes targeting different linkages in plant polysaccharides. The majority of these enzymes have not been functionally char...
ORGANISM(S): Myceliophthora heterothallica 
2016-02-25 | PXD003130 | Pride
Saccharification Progeny Sugar beep pulp Cazy enzymes Myceliophthora heterothallica Plant biomass 
UnknownLow cost sample preparation method using ultrasound for the determination of environmentally critical elements in seaweed.
Not available
S-EPMC10848136 | biostudies-literature
UnknownThe Persistence of Hydrogen Bonds in Pyrimidinones: From Solution to Crystal.
Not available
S-EPMC11450830 | biostudies-literature
TranscriptomicsTranscripts and metabolites of grape ripening and aroma development
Grapes (Vitis species) are economically the most important fruit crop worldwide. However, the complexity of molecular and biochemical events that lead to the onset of ripening in berries as well as how aroma is developed are aspects not fully understood. In an attempt to identify the common mechan...
ORGANISM(S): Vitis vinifera 
2012-10-30 | E-GEOD-35172 | biostudies-arrayexpress
MetabolomicsSerum Predose Metabolic Profiling For Prediction Of Rosuvastatin Pharmacokinetic Parameters In Healthy Volunteers
Rosuvastatin is a quite known lipid-lowering agent generally used for hypercholesterolemia treatment and coronary artery diseases prevention. There is substantial inter-individual variability in the absorption of statins usually caused by genetic polymorphisms leading to variation in the correspondi...
2021-10-29 | MTBLS3128 | MetaboLights
Proteomicsgrape leaves polyphenols inhibit breast cancer malignancy
We tested the inhibitory effects of hydroalcoholic extracts from grape leaves in breast cancer malignancy using MCF-7 and SKBR-3 cell lines.
ORGANISM(S): Homo sapiens (Human) 
2020-05-27 | PXD016748 | Pride
Polyphenols Breast cancer 
UnknownA one-dimensional coordination polymer constructed from isatine-3-oximate and sodium.
Not available
S-EPMC3120341 | biostudies-literature
UnknownBenchmarking Machine Learning Algorithms for Microbial Electromethanogenesis: A Comprehensive Assessment with SHapley Additive exPlanation-Based Insights.
Not available
S-EPMC12801386 | biostudies-literature
GenomicsChronic growth factor signaling in Acute Myeloid Leukemia is connected to a specific chromatin signature [ChIP-Seq]
We performed genome-wide DNaseI hypersensitive site in FLT3-ITD and WT patient samples. We report corresponding gene expression, promoter methylation patterns of differential DHSs as well as differentially occupied TF binding motifs using surrounding DNAseI cut profiles. We examined association patt...
ORGANISM(S): Homo sapiens 
2015-07-03 | E-GEOD-64862 | biostudies-arrayexpress
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