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MetabolomicsExposomic Biomonitoring of Polyphenols by Non-Targeted Analysis and Suspect Screening

Polyphenols, prevalent in plants and fungi, are investigated intensively in nutritional and clinical settings because of their beneficial bioactive properties. Due to their complexity, analysis with untargeted approaches is favorable, which typically use high-resolution mass spectrometry (HRMS) r...

2025-08-07 | MTBLS7564 | MetaboLights
MetabolomicsHost: Microbiome co-metabolic processing of dietary polyphenols – An acute, single blinded, cross-over study with different doses of apple polyphenols in healthy subjects
Apples are one of the most commonly consumed fruits and their high polyphenol content is considered one of the most important determinants of their health-promoting activities. Here we studied the nutrikinetics of apple polyphenols by UHPLC-HRMS metabolite fingerprinting, comparing the bioavailabili...
2018-10-11 | MTBLS473 | MetaboLights
MetabolomicsTwo apples a day modulate human:microbiome co-metabolic processing of polyphenols, tyrosine and tryptophan

PURPOSE: Validated biomarkers of food intake (BFIs) have recently been suggested as a useful tool to assess adherence to dietary guidelines or compliance in human dietary interventions. Although many new candidate biomarkers have emerged in the last decades for different foods fr...

2020-04-28 | MTBLS469 | MetaboLights
MetabolomicsComposite polyphenols mitigate microplastic exposure-related immune disturbances: a two-phase population trial

As people are being widely exposed to microplastics (MPs), it is urgent to elucidate their toxicity mechanisms and identify intervention strategies to mitigate their adverse effects. This study firstly designed a two-phase population trial, comprising a pilot population (n = 151) to investigate t...

2026-08-01 | MTBLS12863 | MetaboLights
MetabolomicsLongitudinal Integration of Microbiota and Metabolomics Reveals Polyphenols-Driven Gut Ecosystem Dynamics
The gut microbiota and its """"""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""theatre of activi...
2026-07-03 | MTBLS14779 | MetaboLights
MetabolomicsExploring the interactions between polyphenols in the fermented grains of sauce-flavor Baijiu and Saccharomyces cerevisiae based on transcriptomic and metabolomic approaches
Polyphenols are abundant in the raw materials (sorghum and wheat) used for sauce-flavor Baijiu fermentation, yet their interactions with the key brewing microorganism (Saccharomyces cerevisiae), remain poorly characterized. This study employed integrated transcriptomic and metabolomic approaches to ...
2026-06-29 | MTBLS14885 | MetaboLights
MetabolomicsA multi-omic profiles of fruits regarding the maturation of Olive (Olea europaea L.) (Polyphenols UPLC-MS assay)
Olive (Olea europaea) has a long history of medicinal and nutritional values own to it rich in polyphenol and fatty acids (FAs) in fruits. In order to better understand the biosynthesis important of these metabolites, we generated comprehensive Iso-Seq full-length and illumina RNA-seq tr...
2019-05-07 | MTBLS814 | MetaboLights
TranscriptomicsNuclear receptor-mediated alleviation of alcoholic fatty liver by polyphenols contained in alcoholic beverages
To elucidate the effect of the polyphenols contained in alcoholic beverages on the metabolic stress induced by ethanol consumption, four groups of mice were fed for five weeks on Lieber's diet with or without ethanol, with ethanol plus ellagic acid, and with ethanol plus trans-resveratrol. Alcoholic...
ORGANISM(S): Mus musculus 
2014-02-01 | E-GEOD-52644 | biostudies-arrayexpress
TranscriptomicsPolyphenols protection against fructose overload
To decipher the beneficial effects of Polyphenols on health, healthy volunteers were randomized into two groups and were submitted to either a red grape polyphenol rich extract supplemented diet (PP) or a placebo diet (PCB) during 8 weeks. Then they were submitted to a fructose load (3g/kg Fat Free ...
ORGANISM(S): Homo sapiens 
2013-02-04 | E-GEOD-35764 | biostudies-arrayexpress
GenomicsRNA-seq for polyphenols treated Pseudomonas syringae
RNA-seq for polyphenols treated Pseudomonas syringae
PRJNA673390 | ENA
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