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GenomicsGenome-wide MAF1-dependent regulation of RNA polymerase III transcription [DamIP-Seq]
In higher eukaryotes, an important mechanism to tune translation in different tissues and conditions is mTORC1-dependent regulation of tRNAs transcription by RNA polymerase III (Pol III), as the relative amount of tRNAs tightly coordinates with the translational needs of the cell. mTORC1 contributes...
ORGANISM(S): Homo sapiens 
2016-02-15 | E-GEOD-73928 | biostudies-arrayexpress
GenomicsThe SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators - ChIP-seq
The heptarepeats of the C-terminal domain of Pol II are extensively modified throughout the transcription cycle. The CTD coordinates RNA synthesis and processing by recruiting transcription regulation factors as well as RNA capping, splicing and 3’end processing factors. The SPOC domain of PHF3 was ...
ORGANISM(S): Homo sapiens 
2023-02-22 | E-MTAB-11506 | biostudies-arrayexpress
GenomicsDynamic BRG1 Recruitment During T Helper Differentiation And Activation Reveals Distal Regulatory Elements
We found binding of the remodeling protein BRG1 was programmed by lineage and activation signals. BRG1 binding was positively correlated with gene activity at protein-coding and miRNA genes. BRG1 binding was found at promoters and distal regions, including known and novel distal regulatory element...
ORGANISM(S): Mus musculus 
2011-03-01 | E-GEOD-23719 | biostudies-arrayexpress
UnknownAssociation Between Migraine and Cervical Artery Dissection: The Italian Project on Stroke in Young Adults.
Not available
S-EPMC5822194 | biostudies-literature
UnknownHistory of Migraine and Volume of Brain Infarcts: The Italian Project on Stroke at Young Age (IPSYS).
Not available
S-EPMC6780016 | biostudies-literature
GenomicsChIPseq profile of RNA polymerase (pol II), the p65 subunit of NFkB, STAT1 and STAT2 in bone marrow derived macrophages after treatment with IFNb, heat-killed Listeria monocytogenes (hkL), or both.
Using ChIP-Seq analysis we define genes induced in macrophages through synergistic transcriptional activation by NFkB and the IFNb-activated transcription factor ISGF3.
ORGANISM(S): Mus musculus 
2015-06-15 | E-MTAB-2972 | biostudies-arrayexpress
TranscriptomicsMechanisms Establishing TLR4-Responsive Activation States of Inflammatory Response Genes (Agilent expression data)
Precise control of the innate immune response is required for resistance to microbial infections and maintenance of normal tissue homeostasis. Because this response involves coordinate regulation of hundreds of genes, it provides a powerful biological system to elucidate the molecular strategies tha...
ORGANISM(S): Mus musculus 
2011-01-01 | E-GEOD-23620 | biostudies-arrayexpress
UnknownFactors Associated With Real-Life Functioning in Persons With Schizophrenia in a 4-Year Follow-up Study of the Italian Network for Research on Psychoses.
Not available
S-EPMC7876615 | biostudies-literature
UnknownEpidemiology, ventilation management and outcomes of COVID-19 ARDS patients versus patients with ARDS due to pneumonia in the Pre-COVID era.
Not available
S-EPMC11330602 | biostudies-literature
UnknownSterile inflammation via TRPM8 RNA-dependent TLR3-NF-B/IRF3 activation promotes antitumor immunity in prostate cancer
Not available
S-SCDT-10_1038-S44318-024-00040-5 | biostudies-other
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