Sort   by:  
 Page size 
TranscriptomicsscRNA-seq study of hippocampal microglia, perivascular macrophages and perivascular fibroblasts in pre-plaque APP-KI mice
Aim of this experiment was to characterize whether SPP1 released from the hippocampal perivascular space could imprint microglia transcriptional states. We performed scRNA-seq analysis on sorted CD140a+ perivascular fibroblast (PVF), CD45highCD11intCD206+ perivascular macrophage (PVM) and CD45intCD1...
ORGANISM(S): Mus musculus 
2024-02-09 | E-MTAB-11918 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA sequencing of self-maintaining lamina propria macrophages
Single-cell RNA sequencing of 697 YFP+ CD64+ lamina propria macrophages isolated from Cx3cr1CreERT2.Rosa26-LSL-YFP mice 35 weeks after tamoxifen administration
ORGANISM(S): Mus musculus 
2018-07-30 | E-MTAB-6976 | biostudies-arrayexpress
ProteomicsIntestinal Macrophages Modulate Brain Synucleinopathy in Parkinson’s disease
Emerging evidence suggests that Parkinson’s disease (PD) may have its origin in the enteric nervous system (ENS), from where alpha-synuclein (αS) pathology spreads to the brain. Decades before the onset of motor symptoms, PD patients suffer from constipation and present with circulating T cells that...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-09 | PXD069218 | Pride
Alpha-synuclein Parkinson's disease Dia Macrophages 
TranscriptomicsBulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages
Self-maintaining gMacs are present in the submucosal and myenteric plexus of the intestine where they maintain enteric neurons and submucosal vasculature YFP-positive and YFP-negative CD11b+, CD64+ macrophages were sorted from lamina propria and muscularis externa of Cx3cr1CreERT2.Rosa26-LSL-YFP ani...
ORGANISM(S): Mus musculus 
2018-07-30 | E-MTAB-6977 | biostudies-arrayexpress
TranscriptomicsscRNA-seq analysis of lung CD64-expressing mononuclear cells, patrolling and classical monocytes from steady-state C57BL/6J mice
We sought to evaluate in an unbiased way the heterogeneity of lung interstitial macrophages and their relationship with alveolar macrophages, lung Ly-6Chi classical monocytes and Ly-6Clo patrolling monocytes, by single cell RNA-Seq.
ORGANISM(S): Mus musculus 
2019-07-31 | E-MTAB-7678 | biostudies-arrayexpress
TranscriptomicsCell-type specific phenotypic characterization of Lyve1+ perivascular macrophages and Sall1+ microglia pooled from PBS and amyloid-β-injected mice
RiboTag-based translatome analysis of pooled oAβ and PBS-challenged brain homogenates of Cx3cr1ccre:Lyve1ncre (n=8 mice) and Cx3cr1ccreSall1ncre:RiboTag-mice (n=4 mice).
ORGANISM(S): Mus musculus 
2023-01-10 | E-MTAB-12515 | biostudies-arrayexpress
Sort   by:  
 Page size