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The maternal mRNA nanos is required for anterior-posterior patterning in the early Drosophila melanogaster development. The nanos-mRNA is translationally repressed and deadenylated during the first two hours of embryogenesis. A stem-loop structure in the 3'-UTR of this RNA (SRE - Smaug recogniiton e...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2017-07-18 | PXD006596 | Pride
Recent findings indicate that the translation elongation rate influences mRNA stability. One of the factors that has been implicated in this link between mRNA decay and translation speed is the yeast DEAD-box helicase Dhh1p. Here, we demonstrate that the human ortholog of Dhh1p, DDX6, triggers deade...
ORGANISM(S): Homo sapiens 
2024-01-23 | GSE231964 | GEO
Human DDX6 regulates translation and decay of inefficiently translated mRNAs
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