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Palaeoproteomic analysis of skeletal elements is increasingly used to study topics such as human evolution. However, many of the skeletal elements that are analysed have been stored and handled over long time periods, and have therefore accumulated contaminating proteins, which may complicate analys...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) Equus caballus (Horse) 
2025-04-24 | PXD050393 | Pride
Benchmarking MicrobIEM - a user-friendly tool for decontamination of microbiome sequencing data
Archaeological materials will accumulate contamination from sources such as handling and storage, which may affect downstream analyses. For dental enamel, it has often been assumed that removal of contamination is not necessary prior to palaeoproteomic analyses, due to the extraction protocols that ...
ORGANISM(S): Coelodonta antiquitatis (woolly rhinoceros) 
2025-12-15 | PXD064417 | Pride
Contamination is a potential issue in palaeoproteomic studies of human evolution, as it may mask low-abundance endogenous proteins and introduce modern variation into the reconstructed ancient proteome. This contamination may stem from many sources, such as the burial environment, storage facilities...
ORGANISM(S): Homo 
2025-04-24 | PXD050370 | Pride
Ambient RNA contamination in single-cell RNA sequencing introduces exogenous transcripts from lysed cells, distorting cell-type annotation and biological interpretation. We performed a systematic benchmark of 7 decontamination tools using datasets with well-defined ground truth. Our evaluation acros...
ORGANISM(S): Mus musculus 
2026-08-10 | GSE337237 | GEO
Systematic Benchmarking of Ambient RNA decontamination Tools to Advance Precision in Single-Cell transcriptomic analysis
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