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TranscriptomicsThe long noncoding RNA HOTAIR has tissue and cell type dependent effects on HOX gene expression and phenotype of cancer cells
HOTAIR was found to be overepressed in a subset of urothelial cancer tissues and cell lines compared to normal controls. Ectopic HOTAIR expression in urothelial cancer cells in vitro demonstrated cell type dependent changes in phenotype. While some cell lines showed increased proloferation activity ...
ORGANISM(S): Homo sapiens 
2015-06-05 | E-GEOD-57672 | biostudies-arrayexpress
TranscriptomicsExpression data of IL-18 generated murine NK cells
We analyzed gene expression profiles of IL-18 generated murine NK cells in comparison to unstimulated, freshly isolated splenic NK cells. We identified a set of 1414 Affymetrix probe sets showing significant misregulation (Welch's T-test, p<0.05; Benjamini-Hochberg FDR corrected). IL-18 generated as...
ORGANISM(S): Mus musculus 
2012-07-10 | E-GEOD-33627 | biostudies-arrayexpress
UnknownSynthetic gestagens exert differential effects on arterial thrombosis and aortic gene expression in ovariectomized apolipoprotein E-deficient mice.
Not available
S-EPMC4253454 | biostudies-literature
TranscriptomicsHost cell responses to persistent mycoplasmas--different stages in infection of HeLa cells with Mycoplasma hominis
M. hominis adherence, colonisation and invasion of HeLa cells were characterised in a time-course study using microarray-based analysis of the HeLa cell transcriptome: 0 h to monitor the baseline of transcription, 4 h to examine host reactions to mycoplasma attachment, 48 h to capture in addition th...
ORGANISM(S): Homo sapiens 
2014-02-06 | E-GEOD-54698 | biostudies-arrayexpress
UnknownCooperative and distinct functions of MK2 and MK3 in the regulation of the macrophage transcriptional response to lipopolysaccharide.
Not available
S-EPMC6667695 | biostudies-literature
TranscriptomicsExpression data from glioma cells exposed to interferon (IFN)-beta
Glioma cells are sensitized to the alkylator temozolomide after exposure to IFN-beta. In glioma-initiating cells (GIC), IFN-beta alone reduces clonogenicity. We investigated differentially expressed genes with or without IFN exposure in either longterm glioma cells or GIC. We used microarrays to inv...
ORGANISM(S): Homo sapiens 
2014-03-31 | E-GEOD-53213 | biostudies-arrayexpress
UnknownValidation of a novel Mho microarray for a comprehensive characterisation of the Mycoplasma hominis action in HeLa cell infection.
Not available
S-EPMC5533444 | biostudies-literature
UnknownHost cell responses to persistent mycoplasmas--different stages in infection of HeLa cells with Mycoplasma hominis.
Not available
S-EPMC3543322 | biostudies-literature
TranscriptomicsDeletion of hyaluronan synthase 3 inhibits neointimal hyperplasia
Affymetrix Mouse Gene 2.0 ST Gene Expression Microarrays were used to analyze differentially expressed genes after carotid artery ligation. The aim of this experiment was to detect genes regulated in Has3 deficient as compared to wildtype controls that might be involved in neointimal hyperplasia. Ne...
ORGANISM(S): Mus musculus 
2015-11-24 | E-GEOD-70410 | biostudies-arrayexpress
Unknownβ-Myosin heavy chain variant Val606Met causes very mild hypertrophic cardiomyopathy in mice, but exacerbates HCM phenotypes in mice carrying other HCM mutations.
Not available
S-EPMC4086907 | biostudies-literature
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