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MetabolomicsMulti-omics integration analysis reveals metabolic changes during sika deer antler growth

Background: Antler is an important economic trait of sika deer (Cervus nippon), capable of rapid growth without signs of tumorigenesis. However, the molecular mechanisms underlying its unique growth pattern remain poorly understood. This study conducted a combined transc...

2026-04-01 | MTBLS12622 | MetaboLights
Proteomicscomparative proteomics of deer antler
we used proteomic technology to disclose the difference of antler regeneration between red deer and sika deer. Through functional analysis, we obtained differentially expressed proteins and the pathway involved in antler regeneration between two groups
ORGANISM(S): Cervus elaphus elaphus Cervus nippon nippon 
2019-06-18 | PXD012090 | Pride
Deer antler  proteomics  regeneration 
ProteomicsProfiling of sika deer antler proteins at different developmental stages based on label-free
We used label-free proteomics approach to analyze the protein expression dynamics of the antler tip in 6 developmental periods (15, 25, 45, 65, 100 and 130 days after the previous antler cast) and costal cartilage. the stages special proteins and differentially expressed proteins (DEPs) in different...
ORGANISM(S): Cervus nippon hortulorum 
2021-09-10 | PXD024323 | Pride
Lc-msms Antler Sika deer 
TranscriptomicsGene Expression Analysis of Deer Antler
Identification of the changes in gene expression between the antler velvet and mesenchyme, pedicle skin and frontal skin tissues from adult male deers (Cervus elaphus). Hybridization data were analysed using MAS5, RMA, GCRMA and Dchip algorithms to maximize the chances of identifying gene expression...
ORGANISM(S): Cervus elaphus 
2010-12-31 | E-GEOD-20036 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of sika deer antler-tip during the ossification stage
To obtain an overview of the antler tip gene expression profile during rapid growth period, a cDNA sample was prepared from antler tip and sequenced using the Illumina sequencing platform.
ORGANISM(S): Cervus nippon 
2011-10-25 | E-MTAB-802 | biostudies-arrayexpress
ProteomicsIntegrative analyses of antler cartilage transcriptome and pro-teome of Gansu red deer (Cervus elaphus kansuensis) at different growth stages
The velvet antler is a unique model for cancer and regeneration research due to its periodic re-generation and rapid growth. Antler growth is mainly triggered by the growth center located in its tip, which consists of velvet skin, mesenchyme and cartilage. Among them, cartilage accounts for most of ...
ORGANISM(S): Cervus elaphus kansuensis 
2022-05-20 | PXD032668 | Pride
Cervus elaphus kansuensis  endochondral ossification  rapid growth   histogenesis  multi-omics 
ProteomicsDeer antler regenerative stem cell tissues LC-MS/MS
As the only known mammalian organ that can fully and annually regenerate, deer antler has significant advantages over lower-order animal models when investigating the control of stem cell-based organ regeneration. Antler regeneration is known to be initiated and maintained by neural crest-derived st...
ORGANISM(S): Cervus Elaphus 
2019-12-19 | PXD016824 |
TranscriptomicsSequencing and de novo analysis of the Chinese Sika deer antler-tip transcriptome during the ossification stage using Illumina RNA-Seq Technology
To obtain an overview of the antler tip gene expression profile during the ossification stage, a cDNA sample was prepared from antler tip and sequenced using the Illumina sequencing platform.
ORGANISM(S): Cervus nippon 
2012-11-02 | E-MTAB-853 | biostudies-arrayexpress
UnknownSingle-cell transcriptome reveals core cell populations and androgen-RXFP2 axis involved in deer antler full regeneration.
Not available
S-EPMC9772379 | biostudies-literature
TranscriptomicsIdentifying deer antler proliferation and mineralization genes using comparative RNA-seq
Purpose: The goal of this study is to compare (RNA-seq) transcriptomes of in vitro cultured human bone marrow-derived mesenchymal stem cells (hMSCs) and fallow deer antler-derived skeletal progenitors (FD RM Cells) under multiple conditions to identify candidate proliferation and mineralization gene...
ORGANISM(S): Homo sapiens Dama dama 
2018-11-16 | GSE89796 | GEO
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