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ProteomicsCX-MS of TFIIH and Def1 complex
The DNA damage response is an essential process for the survival of living cells. In a subset of stress-responsive genes in humans,Elongin controls transcription in response to multiple stimuli, such as DNA damage, oxidative stress, and heat shock. Yeast Elongin (Ela1-Elc1), along with Def1, is know...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-10-22 | PXD008223 | Pride
Stress response Transcription Rna polymerase ii Tfiih Def1 
OtherGene expression analysis and proximity labeling reveal posttranscriptional functions of the yeast RNA Polymerase II regulator Def1
Def1 is a yeast protein that promotes transcription elongation and regulates the degradation of RNA polymerase II during transcription stress. Although Def1 is localized in the cytoplasm, its functions in this cellular compartment are not yet understood. Despite its well-established roles in transcr...
ORGANISM(S): Saccharomyces cerevisiae 
2026-01-21 | GSE290861 | GEO
GenomicsGene expression analysis and proximity labeling reveal posttranscriptional functions of the yeast RNA Polymerase II regulator Def1
Gene expression analysis and proximity labeling reveal posttranscriptional functions of the yeast RNA Polymerase II regulator Def1
PRJNA1230277 | ENA
UnknownDef1 interacts with TFIIH and modulates RNA polymerase II transcription.
Not available
S-EPMC5740667 | biostudies-literature
UnknownProteasome-mediated processing of Def1, a critical step in the cellular response to transcription stress.
Not available
S-EPMC3778974 | biostudies-literature
UnknownDegradation factor 1, Def1, regulates mRNA translation and decay through Ccr4-Not-dependent ubiquitylation of the ribosome.
Not available
S-EPMC12710963 | biostudies-literature
UnknownGene expression analysis and proximity labeling reveal post-transcriptional functions of the yeast RNA polymerase II regulator Def1.
Not available
S-EPMC12804109 | biostudies-literature
UnknownDef1 and Dst1 play distinct roles in repair of AP lesions in highly transcribed genomic regions.
Not available
S-EPMC5815317 | biostudies-literature
UnknownRNA polymerase II transcription attenuation at the yeast DNA repair gene DEF1 is biologically significant and dependent on the Hrp1 RNA-recognition motif.
Not available
S-EPMC9836349 | biostudies-literature
UnknownThe intergenic region of the maize defensin-like protein genes Def1 and Def2 functions as an embryo-specific asymmetric bidirectional promoter.
Not available
S-EPMC5301941 | biostudies-literature
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