Defective deep placentation

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Ministry of Education-Shanghai Key Laboratory of Children’s Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine (1)

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Expression changes of proteins associated with the development of preeclampsia in maternal plasma: a case control study

Defective deep placentation, an abnormal transformation of the spiral arteries in the junctional zone of the myometrium, is known to cause significant obstetrical complications such as preeclampsia (PE), fetal growth restriction, and placental infarcts with fetal death. Serological biomarkers to pre...

ORGANISM(S): Homo sapiens (Human)

2018-07-05 | PXD003419 | Pride

Serum proteomic analysis of the great obstetrical syndromes

The great obstetrical syndromes (GOS) encompass a spectrum of pregnancy-related complications associated with defective deep placentation, including hypertensive pregnancies, preterm birth, and fetal growth restriction. We performed pre-symptomatic phase proteomic profiling of serum samples from 384...

ORGANISM(S): Homo sapiens (Human)

2025-08-22 | PXD066032 | Pride

Human serum pregnancy

Arid3a is required for mammalian placenta development

Previous studies in the mouse indicated that Arid3a plays a critical role in the first cell fate decision required for generation of trophectoderm (TE). Here, we demonstrate that Arid3a is widely expressed during mouse and human placentation and essential for early embryonic viability. Arid3a is loc...

ORGANISM(S): Mus musculus

2016-07-01 | E-GEOD-79638 | biostudies-arrayexpress

Vasoactive Intestinal Peptide modulates trophoblast-derived cell line function and interaction with phagocytic cells through autocrine pathways.

Not available

S-EPMC4876379 | biostudies-literature

Porphyromonas gingivalis strain-dependent inhibition of uterine spiral artery remodeling in the pregnant rat.

Not available

S-EPMC6297315 | biostudies-literature

Pre-eclampsia part 1: current understanding of its pathophysiology.

Not available

S-EPMC5893150 | biostudies-literature

Long-Term Consequences of Placental Vascular Pathology on the Maternal and Offspring Cardiovascular Systems.