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UnknownClinical Benefits of Olaparib in Mexican Ovarian Cancer Patients With Founder Mutation BRCA1-Del ex9-12.
Background: Ovarian cancer (OC) is gynecologic cancer with the highest mortality rate. It is estimated that 13-17% of ovarian cancers are due to heritable mutations in BRCA1 and BRCA2. The BRCA1 (BRCA1-Del ex9-12) Mexican founder mutation is responsible for 28-35% ...
S-EPMC9207274 | biostudies-literature
UnknownNaringenin mitigates autoimmune features in lupus-prone mice by modulation of T-cell subsets and cytokines profile.
Naringenin is flavonoid mainly found in citrus fruits which has shown several biological properties. In this work, we evaluated the therapeutic potential of the flavonoid Naringenin. Five-month-old B6.MRL-Faslpr/J lupus-prone mice were administered daily orally with Naringenin for seven months. We s...
S-EPMC7233587 | biostudies-literature
UnknownComprehensive Chemical and Sensory Assessment of Wines Made from White Grapes of Vitis vinifera Cultivars Albillo Dorado and Montonera del Casar: A Comparative Study with Airen.
The ability to obtain different wines with a singular organoleptic profile is one of the main factors for the wine industry's growth, in order to appeal to a broad cross section of consumers. Due to this, white wines made from the novel grape genotypes Albillo Dorado and Montonera del Casar (Vitis v...
S-EPMC7556037 | biostudies-literature
UnknownProsopis juliflora Seed Waste as Biochar for the Removal of Blue Methylene: A Thermodynamic and Kinetic Study.
In this work, we studied the methylene blue (MB) dye adsorption capacity on biochar derived from residues of Prosopis juliflora seed waste, a species found in the region of the tropical dry forest of Piojó in the Department of Atlántico, Colombia. The materials were obtained by pyrolysis at t...
S-EPMC9713793 | biostudies-literature
UnknownSimultaneous quantification of lead, cadmium and zinc in superficial marine sediments using a carbon-fiber microelectrode modified with bismuth film.
Marine sediments are a useful environmental assessment matrix as they naturally trap toxic substances of anthropogenic origin and thus have higher concentrations of these than the surrounding water. Therefore, developing methods for the sensitive, accurate, and inexpensive quantification of these su...
S-EPMC10658076 | biostudies-literature
UnknownSmall Molecules Derived from Thieno[3,4-c]pyrrole-4,6-dione (TPD) and Their Use in Solution Processed Organic Solar Cells.
In this work, microwave synthesis, chemical, optical and electrochemical characterization of three small organic molecules, TPA-TPD, TPA-PT-TPD and TPA-TT-TPD with donor-acceptor structure and their use in organic photovoltaic cells are reported. For the synthesis, 5-(2-ethylhex...
S-EPMC6151745 | biostudies-literature
UnknownFeasibility and impact of Creciendo Sanos, a clinic-based pilot intervention to prevent obesity among preschool children in Mexico City.

Background

Mexico has the highest adult overweight and obesity prevalence in the Americas; 23.8% of children <5 years old are at risk for overweight and 9.7% are already overweight or obese. Creciendo Sanos was a pilot intervention to prevent obesity among preschoolers in Instituto Mexicano ...
S-EPMC3999907 | biostudies-literature
UnknownFAIR occurrence data for disease vectors in Paraguay: provenance, quality, and reuse potential (1998-2023).
This article describes a nationwide, georeferenced entomological dataset of disease vectors compiled from the historical archives of the Servicio Nacional de Erradicación del Paludismo (SENEPA) in Paraguay from 1998 to 2023. The dataset consolidates 20,619 standardized occurrence records derived fro...
S-EPMC13632199 | biostudies-literature
UnknownCoordinate loss of MAP3K7 and CHD1 promotes aggressive prostate cancer.
Prostate cancer subtypes are poorly defined and functional validation of drivers of ETS rearrangement-negative prostate cancer has not been conducted. Here, we identified an ETS(-) subtype of aggressive prostate cancer (ERG(-)MAP3K7(del)CHD1(del)) and used a novel developmental model and a cell line...
S-EPMC4531265 | biostudies-literature
UnknownDetection of Possible Resistance Mechanisms in Uropathogenic <i>Escherichia coli</i> Strains Isolated from Kidney Transplant Recipients Based on Whole Genome Sequencing.

Background

Urinary tract infections are a global health concern, with uropathogenic Escherichia coli (UPEC) accounting for 80-90% of cases. Given the rise in antimicrobial resistance, our aim was to elucidate the genetic mechanisms behind low-level resistance to ciprofloxacin and fosf...
S-EPMC11853403 | biostudies-literature
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