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ProteomicsCancer Associated Fibroblast-FAK regulates malignant cell metabolism
Breast and pancreatic cancers are characterised by profound metabolic changes1,2. Until recently, these changes have been ascribed to their intrinsic genetic profiles2-4. However, the contribution of cancer-associated fibroblasts (CAFs) to cell metabolism has not been fully investigated5. Here, we p...
ORGANISM(S): Mus musculus (Mouse) 
2020-02-18 | PXD008276 | Pride
Fak Metabolism Fibroblast 
UnknownOutcomes of organ-sparing surgery for adult testicular tumors: A systematic review of the literature.
Not available
S-EPMC8462801 | biostudies-literature
ProteomicsLow endothelial cell FAK expression reduces pancreatic ductal adenocarcinoma liver metastasis after gemcitabine treatment
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers with a high level of liver metastasis. Despite substantial advances, resistance to therapy, including gemcitabine, is still a major obstacle to improved progression free survival. Recent studies have indicated that endothe...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-10 | PXD021542 | Pride
Endothelium Chemotherapy Focal adhesion kinase Tumour models Resistance Gemcitabine Phosphoproteomics Metastasis Pancreatic ductal adenocarcinoma Lc-ms/ms 
UnknownNeuroinflammation in the normal-appearing white matter (NAWM) of the multiple sclerosis brain causes abnormalities at the nodes of Ranvier.
Not available
S-EPMC7769608 | biostudies-literature
ProteomicsCancer burden is controlled by mural cell- β3-integrin regulated crosstalk with tumor cells
Phosphoproteomics analysis were performed in WT and β3-integrin-null pericytes. On the other hand, phosphoproteomics experiments were done in B16F0 melanoma cells treated for 24 hours with conditioned medium from WT and β3-integrin-null pericytes.
ORGANISM(S): Mus musculus (Mouse) 
2020-06-01 | PXD014513 | Pride
Paracrine Β3-integrin Mural-cell 
UnknownCancer associated fibroblast FAK regulates malignant cell metabolism.
Not available
S-EPMC7064590 | biostudies-literature
UnknownRelationship Between Severity of Ischemia and Coronary Artery Disease for Different Stress Test Modalities in the ISCHEMIA Trial.
Not available
S-EPMC11658795 | biostudies-literature
UnknownSARS-CoV-2 Viral Load in the Nasopharynx at Time of First Infection Among Unvaccinated Individuals: A Secondary Cross-Protocol Analysis of 4 Randomized Trials.
Not available
S-EPMC11117088 | biostudies-literature
UnknownSustained Performance of Cardiac Arrest Prevention in Pediatric Cardiac Intensive Care Units.
Not available
S-EPMC11385048 | biostudies-literature
UnknownPreventing Cardiac Arrest in the Pediatric Cardiac Intensive Care Unit Through Multicenter Collaboration.
Not available
S-EPMC9257678 | biostudies-literature
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