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ProteomicsA novel paracrine induction of RNA Granules by Feline Calicivirus
We are here presenting a new paracrine induction of RNA granules by viruses. Infection by viruses imposes major stress on the host cell. In response to this stress, infected cells can induce several defence mechanisms, which include the activation of stress response pathways and the innate immune re...
ORGANISM(S): Felis catus (Cat) (Felis silvestris catus) 
2022-03-14 | PXD021881 | Pride
Paracrine Fcv G3bp1 Stress granules 
ProteomicsParacrine Signaling in Visceral Fat
Accumulation of visceral (VIS) as opposed to subcutaneous (SUB) fat is a predictor of metabolic disorders, insulin resistance, and cardiovascular disease. This is due in part to the limited capacity of VIS fat to buffer lipids allowing them to deposit in insulin-sensitive tissues, thus impairing ins...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-21 | PXD014672 | Pride
Paracrine signaling Mouse Visceral fat 
TranscriptomicsArginine utilization following mycobacteria infection in macrophages is dependent on autocrine-paracrine signaling
Nitric oxide (NO) produced by macrophages (MØs) is toxic to both host tissues and invading pathogens and its regulation is therefore essential to suppress host cytotoxicity. MØ arginase 1 (Arg1) inhibits NO production by competing with NO synthases for arginine, the common substrate of NO synthases ...
ORGANISM(S): Mus musculus 
2010-07-14 | E-GEOD-22935 | biostudies-arrayexpress
TranscriptomicsContribution of paracrine signalling on dendritic cell activation
The physiological function of the immune system and the response to therapeutic immunomodulators may be sensitive to combinatorial cytokine micro-environments that shape the responses of specific immune cells. Previous work shows that paracrine cytokines released by virus-infected human dendritic ce...
ORGANISM(S): Homo sapiens 
2013-12-15 | E-GEOD-52081 | biostudies-arrayexpress
TranscriptomicsCancer-Associated Fibroblasts Support Lung Cancer Stemness through Paracrine IGF-II/IGF1R/Nanog Signaling
The CLS1/CAF co-culture maintained the cancer stemness. This cancer stemness was lost when the CAF feeder cells were removed during passaging. To investigate the specific signaling pathways and markers of lung CSCs, we analyzed the gene expression profile of the CLS1 sphere after CLS1/CAF co-cultur...
ORGANISM(S): Homo sapiens 
2014-03-25 | E-GEOD-38678 | biostudies-arrayexpress
GenomicsInjury Induced Paracrine Effects on the Podocyte’s Transcriptome
Injury Induced Paracrine Effects on the Podocyte’s Transcriptome
PRJNA1075095 | ENA
TranscriptomicsUterine stromal cell_cultured with uNK conditioned Medium
The endometrium contains a distinct population of immune cells consisting of 70% natural killer (NK) cells that undergo cyclic changes during the menstrual cycle. However, how these uterine NK (uNK) cells interact with uterine stromal cells (SC) remains unclear. We therefore investigated the paracri...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-9718 | biostudies-arrayexpress
GenomicsA novel paracrine induction of RNA granules by feline calicivirus
A novel paracrine induction of RNA granules by feline calicivirus
PRJNA720417 | ENA
TranscriptomicsTranscription profiling of human endometrial stromal cells treated with human trophoblasts vs. control, sampled at multiple time points to investigate stromal cell response to paracrine signals from the trophoblast
During the invasive phase of implantation, trophoblasts and maternal decidual stromal cells secrete products that regulate trophoblast differentiation and migration into the maternal endometrium. Paracrine interactions between the extravillous trophoblast and the maternal decidua are important for s...
ORGANISM(S): Homo sapiens 
2007-11-02 | E-GEOD-5809 | biostudies-arrayexpress
GenomicsGene expression profiling of dynamic paracrine senescence in human fibroblasts
Gene expression profiling of dynamic paracrine senescence in human fibroblasts
PRJNA580255 | ENA
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