During classical non-homologous end joining (cNHEJ), DNA-dependent protein kinase (DNA-PK) encapsulates free DNA ends, forming a recruitment platform for downstream end-joining factors including Ligase 4 (LIG4). DNA-PK can also bind telomeres, but does not initiate cNHEJ at this position. How the en...
ORGANISM(S): Homo sapiens (Human)
