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TranscriptomicsTranscription profiling of testis biopsies to investigate testis developmental gene expression in cryptorchid boys at risk of azoospermia
Despite timely and successful surgery, 32% of patients with bilateral and 10% with unilateral cryptorchidism will develop azoospermia. Cryptorchid boys at risk of azoospermia display a typical testicular histology of impaired mini-puberty at the time of the orchidopexy. During mini-puberty increased...
ORGANISM(S): Homo sapiens 
2010-11-23 | E-GEOD-25518 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type and Sox9 knock out mice to study the role of Sox 9 (testis determining gene) after testis induction
To study the role of the testis determining gene Sox9 after testis induction, conditional inactivation of Sox9 was achieved with the help of an AMH-Cre line. Mutant mice are fertile up to about 3 months of age, becoming sterile afterwards. Expression profiles should help to reveal the underlying cau...
ORGANISM(S): Mus musculus 
2010-07-01 | E-TABM-528 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mice mutant for Sox8 and Sox9 has early testicular sterility
To study a possible redundant role of mouse Sox8 and Sox9 after testis induction we generated double mutants by AMH-Cre conditional inactivation of Sox9 in a Sox8-/- background. Double mutants arrest spermatogenesis in early pubescence. We performed expression profiling to explore causes. AMH-Cre/+...
ORGANISM(S): Mus musculus 
2013-01-03 | E-TABM-531 | biostudies-arrayexpress
UnknownRank Difference Analysis of Microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data.
Not available
S-EPMC526220 | biostudies-literature
UnknownMIMAS: an innovative tool for network-based high density oligonucleotide microarray data management and annotation.
Not available
S-EPMC1459208 | biostudies-literature
UnknownFhl5/Act, a CREM-binding transcriptional activator required for normal sperm maturation and morphology, is not essential for testicular gene expression.
Not available
S-EPMC2788571 | biostudies-literature
UnknownAshbya Genome Database 3.0: a cross-species genome and transcriptome browser for yeast biologists.
Not available
S-EPMC1779777 | biostudies-literature
UnknownProfiling spermatogenic failure in adult testes bearing Sox9-deficient Sertoli cells identifies genes involved in feminization, inflammation and stress.
Not available
S-EPMC3024295 | biostudies-literature
UnknownFunctional features of cancer stem cells in melanoma cell lines.
Not available
S-EPMC3765139 | biostudies-literature
UnknownExpression profiling of mammalian male meiosis and gametogenesis identifies novel candidate genes for roles in the regulation of fertility.
Not available
S-EPMC363067 | biostudies-literature
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