Dendritic spines

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Preservation of dendritic spines is a putative mechanism of protection against cognitive impairment despite development of Alzheimer Disease (AD)-related pathologies. Aging, the chief late-onset AD risk factor, is associated with dendritic spine loss in select brain areas. However, no study to our k...

ORGANISM(S): Homo sapiens (Human)

2026-08-07 | PXD057115 | Pride

Caldendrin regulates spine apparatus localization through myosin V-dependent ER-stabilization in dendritic spines

Excitatory synapses of principal hippocampal neurons are frequently located on dendritic spines. The dynamic strengthening or weakening of individual inputs results in a great structural and molecular diversity of dendritic spines. Active spines with large Ca2+-transients are frequently invaded by a...

ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat)

2022-01-27 | PXD029427 | Pride

Spine apparatus Myosin V-dependent er-stabilization Caldendrin Dendritic spines

Imaging Dendritic Spines in Caenorhabditis elegans.

Not available

S-EPMC11296318 | biostudies-literature

Attenuation of Synaptic Potentials in Dendritic Spines.

Not available

S-EPMC5709047 | biostudies-literature

Sleep promotes the formation of dendritic filopodia and spines near learning-inactive existing spines.

Not available

S-EPMC8685900 | biostudies-literature