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TranscriptomicsRNA-seq of retinal organoids derived from RPGR patient-, control- and mutation-corrected-iPSC at different developmental stages
Retinitis pigmentosa (RP) is an irreversible and inherited retinopathy. RPGR mutations are the most common causes of this disease. It remains challenging to decipher the mechanism of RPGR mutation because of the lack of appropriate study models. The substitution of patient-specific diseased retina w...
ORGANISM(S): Homo sapiens 
2020-02-01 | E-MTAB-6490 | biostudies-arrayexpress
MetabolomicsUntargeted metabolomics of purple and orange-fleshed sweet potatoes reveals a large structural diversity of anthocyanins and flavonoids

Anthocyanins are economically valuable phytochemicals of significant relevance to human health. Industrially extracted from multiple fruit and vegetable sources, anthocyanin yield and profiles can vary between sources and growing conditions. In this study, we focused on three purple-fleshed and o...

2021-09-01 | MTBLS2956 | MetaboLights
MetabolomicsDifferential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells
Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
TranscriptomicsGenomic landscape of copy number aberrations enables the identification of oncogenic drivers in hepatocellular carcinoma [tumor]
Cancer is a genetic disease with frequent somatic alterations in DNA. Study of recurrent copy number aberrations (CNAs) in human cancers would enable the elucidation of disease mechanisms and the identification of key oncogenic drivers with causal roles in oncogenesis. We have comprehensively and sy...
ORGANISM(S): Homo sapiens 
2013-05-22 | E-GEOD-38323 | biostudies-arrayexpress
ProteomicsMass spectrometry identification of PPARγ methylation sites
Purified recombinant PPARγ-Flag and PRMT4-His were used for in vitro methyltransferase assay.We separated purified methylated PPARγ proteins by SDS-PAGE, visualized them by staining with Coomassie blue, protein lanes were cut into pieces about 1 mm3, and followed further destained.
ORGANISM(S): Homo Sapiens 
2022-06-27 | PXD034929 |
ProteomicsProteomic Screening of OLP/OLL-EVs
In this project, we first screened proteomics of OLP/OLL tissue-derived extracellular vesiclesEVs
ORGANISM(S): Homo Sapiens 
2021-06-25 | PXD026938 |
TranscriptomicsGenomic landscape of copy number aberrations enables the identification of oncogenic drivers in hepatocellular carcinoma
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-05-22 | E-GEOD-38326 | biostudies-arrayexpress
UnknownThe efficacy and safety of acupuncture combined with language training for motor aphasia after stroke: study protocol for a multicenter randomized sham-controlled trial.
Not available
S-EPMC9245218 | biostudies-literature
TranscriptomicsGenomic landscape of copy number aberrations enables the identification of oncogenic drivers in hepatocellular carcinoma [cell line]
Cancer is a genetic disease with frequent somatic alterations in DNA. Study of recurrent copy number aberrations (CNAs) in human cancers would enable the elucidation of disease mechanisms and the identification of key oncogenic drivers with causal roles in oncogenesis. We have comprehensively and sy...
ORGANISM(S): Homo sapiens 
2013-05-22 | E-GEOD-38207 | biostudies-arrayexpress
ProteomicsLessons from Two Design-Build-Test-Learn Cycles of Dodecanol Production in Escherichia coli Aided by Machine Learning
The Design–Build–Test–Learn (DBTL) cycle, facilitated by exponentially improving capabilities in synthetic biology, is an increasingly adopted metabolic engineering framework that represents a more systematic and efficient approach to strain development than historical efforts in biofuels and bio-ba...
ORGANISM(S): Escherichia Coli 
2019-05-16 | PXD012312 | panorama
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