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ProteomicsMass spectrometry analysis of USP38 interactors
After ectopic expression of Flag-USP38 or an empty vector in HEK293T cells for 48 hours, cells were lysed, and the supernatant after lysis was added to magnetic beads coupled with Flag antibodies. The mixture was incubated at 4°C overnight for pull-down. Subsequently, the magnetic beads were washed ...
ORGANISM(S): Homo Sapiens 
2024-08-26 | PXD055320 |
ProteomicsStructural insights into regulatory mechanism of RNA modification by human m6A-METTL associated complex
N6-methyladenosine (m6A) is the most abundant ribonucleotide modification among the eukaryotic messenger RNAs (mRNAs). The m6A “writer” is composed of an m6A-METTL complex (MAC), the catalytic subunit, and an m6A-METTL associated complex (MACOM), the regulatory subunit essential for the enzymatic ac...
ORGANISM(S): Homo Sapiens 
2022-06-23 | PXD028456 |
ProteomicsIntegrated Omics in Drosophila Uncover Circadian Kinases
Most organisms on the earth exhibit circadian rhythms in behavior and physiology, which are driven by endogenous clocks. Phosphorylation plays a central role in timing the clock, but how this contributes to overt rhythms is unclear. Here we conducted phosphoprotemoics in conjunction with transcripto...
ORGANISM(S): Drosophila Melanogaster 
2018-05-31 | PXD009887 |
ProteomicsProteomics of Mus musculus liver infected with Clonorchis sinensis
The molecular mechanism at the early infection of Clonorchis sinensis
ORGANISM(S): Mus Musculus 
2023-01-07 | PXD039310 |
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