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MetabolomicsTrace elements and lipidomic datasets of stranding samples in the blubber of Turpsios truncatus from the Yucatan Coast: Association with biological features
Trace elements are the result of natural and anthropogenic sources. Some of them are toxic causing alterations in the properties of membranes and produce lipid peroxidation. The dataset presented here is associated with the research article paper entitled “Trace element and lipidomic analysis of bot...
2022-10-24 | MTBLS5772 | MetaboLights
TranscriptomicsThe Genomics of the Fetal Hypothalamic Cellular Response to Transient Hypoxia: Endocrine, Immune, and Metabolic Responses
Fetuses respond to transient hypoxia (a common stressor in utero) with cellular responses that are appropriate for promoting survival of the fetus. The present experiment was performed to identify the acute genomic responses of the fetal hypothalamus to transient hypoxia. Three fetal sheep were ex...
ORGANISM(S): Ovis aries 
2014-01-16 | E-GEOD-43371 | biostudies-arrayexpress
ProteomicsiTRAQ Manatee
In 2013, two large-scale Florida manatee (Trichechus manatus latirostris) mortality episodes were reported on separate coasts of Florida. The east coast mortality episode was associated with an unknown etiology in the Indian River Lagoon (IRL). The west coast mortality episode was attributed to a pe...
ORGANISM(S): Trichechus manatus (Caribbean manatee) (West Indian manatee) 
2021-08-30 | PXD002470 | Pride
Itraq mass spectrometry Manatee 
TranscriptomicsEvaluating the endocrine disrupting impacts of paper mill exposure on the Eastern Mosquitofish (Gambusia holbrooki) by gene expression analysis
Masculinized female Eastern Mosquitofish (Gambusia holbrooki) have resided downstream of paper mills in Florida since the 1980's. The potential impacts of this effluent on the mosquitofish endocrine system are unknown. The objective of this study was to evaluate gene expression patterns of endocrine...
ORGANISM(S): Gambusia holbrooki 
2013-11-01 | E-GEOD-49238 | biostudies-arrayexpress
TranscriptomicsDiet study with EE2 in liver of female largemouth bass (LMB)
17alpha-ethinylestradiol (EE2) is one of the most potent estrogens that have the ability to interfere with the endocrine system of fish. The objective was to investigate the effects and mechanisms of action caused by 60 days of dietary exposure to 0.2 mg EE2/kg and 0.07 mg EE2/kg feed in female larg...
ORGANISM(S): Micropterus salmoides 
2011-03-24 | E-GEOD-28143 | biostudies-arrayexpress
TranscriptomicsGene signaling pathways in liver of largemouth bass by a sub-chronic dietary exposure to EE2
The objective of this study was to investigate pathway signatures altered in the livers of female largemouth bass (LMB) and their potential links with biological responses by dietary exposure to 0.2 mg EE2/Kg (1% of their body weight) over two months using a transcriptomics approach. A high concentr...
ORGANISM(S): Micropterus salmoides 
2014-08-31 | E-GEOD-59224 | biostudies-arrayexpress
TranscriptomicsEffects of a short-term exposure to the fungicide prochloraz on endocrine function and gene expression in female fathead minnows (Pimephales promelas)
Prochloraz is a fungicide known to cause endocrine disruption through effects on the hypothalamic-pituitary-gonadal (HPG) axis. To determine the short-term impacts of prochloraz on gene expression and steroid production, adult female fathead minnows (Pimephales promelas) were exposed to the chemical...
ORGANISM(S): Pimephales promelas 
2011-02-03 | E-GEOD-26958 | biostudies-arrayexpress
TranscriptomicsLargemouth Bass E2 exposure
A novel custom microarray for largemouth bass (Micropterus salmoides) was designed from sequences obtained from a normalized cDNA library using the 454 Life Sciences GS-20 pyrosequencer. The GS-20 yielded in excess of 58 million bases of high-quality sequence. The sequence information was combined...
ORGANISM(S): Micropterus salmoides 
2010-05-25 | E-GEOD-10693 | biostudies-arrayexpress
TranscriptomicsGene expression changes in the female zebrafish (Danio rerio) brain in response to acute exposure to methylmercury
Methylmercury (MeHg) is a potent neurotoxin and endocrine disruptor that accumulates in aquatic systems. Previous studies have shown suppression of hormone levels in both male and female fish, suggesting effects on gonadotropin regulation in the brain. We investigated the gene expression profile in ...
ORGANISM(S): Danio rerio 
2010-09-30 | E-GEOD-22662 | biostudies-arrayexpress
TranscriptomicsGenomics of the ovine fetal brain ontogeny during the last stage of gestation
Normal development in the brain requires temporal changes in gene expression. A better understanding of the genomics of the fetal brain during late gestation can help to improve our understanding of the molecular events that enable the newborn to survive extra-uterine life. The purpose of the prese...
ORGANISM(S): Ovis aries 
2014-06-30 | E-GEOD-50460 | biostudies-arrayexpress
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