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MetabolomicsExploring the Influence of Psychological Factors on the Comorbidity of Dental Caries and Obesity in Adolescents from the Perspective of the Oral-Gut-Brain Axis

This study explores the impact of psychological factors on the comorbidity of dental caries and obesity in adolescents through the oral-gut-brain axis. An epidemiological survey was conducted on 1,024 students from Beizhen No. 1 Junior High School, with 90 adolescents aged 12–15 included in biosa...

2025-08-22 | MTBLS12873 | MetaboLights
TranscriptomicsComparative gene expression analysis of dental follicle and periodontal ligament in humans
The aim of this study was to evaluate and compare the gene expression profiles of dental follicle and periodontal ligament in humans, which can possibly explain their functions of dental follicle and PDL such as eruption coordination and stress resorption. That may apply this information to clinical...
ORGANISM(S): Homo sapiens 
2014-08-21 | E-GEOD-51342 | biostudies-arrayexpress
MetabolomicsExploring the Impact of Sleep Deprivation on the Characteristics and Associations of Oral-Gut Microbiota in Adolescents with Comorbidity of Dental Caries and Obesity
We conducted a cross-sectional study involving 85 adolescents aged 12–15 years, divided into healthy controls (HC), caries-obesity comorbidity (CO), and caries-obesity with sleep deprivation (COS) groups. Oral and fecal samples were collected for 16S rRNA gene sequencing, untargeted metabolomics, an...
2026-04-29 | MTBLS14395 | MetaboLights
TranscriptomicsHypoxia-enhanced Derivation of iPSCs from Human Dental Pulp Cells
Hypoxia enhances the reprogramming efficiency of human dermal fibroblasts to become induced pluripotent stem cells (iPSCs). Because we showed previously that the hypoxia facilitates the isolation and maintenance of human dental pulp cells (DPCs), we examined here whether it promotes the reprogrammin...
ORGANISM(S): Homo sapiens 
2013-09-03 | E-GEOD-45872 | biostudies-arrayexpress
MetabolomicsDistinct signatures of dental plaque metabolic byproducts dictated by periodontal inflammatory status
Not available
ORGANISM(S): Homo sapiens 
ST000496 | MetabolomicsWorkbench
MetabolomicsMulti-omic analysis reveals bacteria may have a role in dental erosion
Not available
ORGANISM(S): Homo sapiens 
ST002265 | MetabolomicsWorkbench
TranscriptomicsComparative gene expression analysis of the human dental pulp in deciduous and permanent teeth
Human deciduous and permanent teeth exhibit different developmental processes, morphologies, histological characteristics and life cycles. In addition their pulp tissues react differently to external stimuli, such as the pulp sensitivity test, dental trauma and pulp therapy materials. These differen...
ORGANISM(S): Homo sapiens 
2014-08-21 | E-GEOD-51449 | biostudies-arrayexpress
ProteomicsMetaproteomic profiling of saliva in subjects with periodontitis, dental caries and orally healthy controls
The composition of the salivary microbiota has been reported to differentiate between patients with periodontitis, dental caries and orally healthy individuals. Thus, the purpose of the present investigation was to compare metaproteomic profiles of saliva in oral health and disease. Stimulated saliv...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080763 | MassIVE
ProteomicsTAILS N-terminomics of the human dental pulp stroma and the odontoblast layer
We report the targeted analysis of the human dental pulp stroma and the odontoblast layer using the positional proteomics technique TAILS N-terminomics, which allowed us to capture both naturally blocked and unblocked protein N-termini, and to identify differences between e.g. the dental pulp proteo...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-10 | MSV000083951 | MassIVE
TranscriptomicsTranscription profiling of human dental pulp stem cells in long term culture
In previous studies, human dental pulp stem cells (hDPSCs) were mainly isolated from adults. In this manuscript, we tried characterization of hDPSCs isolated from an earlier developmental stage to evaluate potential usage of these cells for tissue regenerative therapy. hDPSCs isolated at the crown-c...
ORGANISM(S): Homo sapiens 
2008-04-08 | E-GEOD-10444 | biostudies-arrayexpress
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