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Despite the growing interest in basic research on Euglena gracilis and its importance in bioproduction, several key questions regarding its cell biology remain unanswered. One of them concerns the mechanism of protein import into its secondary chloroplasts, which are derived from a green alga. In th...
ORGANISM(S): Euglena gracilis 
2026-09-28 | PXD073723 | Pride
The accumulation of unfolded proteins in the lumen of the endoplasmic reticulum (ER) causes stress and induces the unfolded protein response (UPR) which is characterised in part by the transcriptional induction of genes involved in assisting protein folding. Translational responses to ER stress have...
ORGANISM(S): Saccharomyces cerevisiae 
West Nile virus (WNV) causes an acute neurological infection attended by massive neuronal cell death. However, the mechanism(s) behind the virus-induced cell death is poorly understood. Using a library containing 77,406 sgRNAs targeting 20,121 genes, we performed a genome-wide screen using CRISPR/Ca...
ORGANISM(S): Homo sapiens 
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