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GenomicsThe cardiac glycoside deslanoside imposes an anticancer effect on prostate cancer involving multiple signaling pathways
The cardiac glycoside deslanoside imposes an anticancer effect on prostate cancer involving multiple signaling pathways
PRJNA764252 | ENA
TranscriptomicsThe cardiac glycoside deslanoside imposes an anticancer effect on prostate cancer involving multiple signaling pathways
Prostate cancer (PCa) is a leading cause of cancer-related deaths among men worldwide, and advanced prostate cancers are mostly incurable. It is urgently needed to find new therapeutic options. Deslanoside is a cardiac glycoside, the efficacy of which on cancers has never been reported. In this stud...
ORGANISM(S): Homo sapiens 
2021-12-07 | GSE184380 | GEO
UnknownThe Cardiac Glycoside Deslanoside Exerts Anticancer Activity in Prostate Cancer Cells by Modulating Multiple Signaling Pathways.
Not available
S-EPMC8616045 | biostudies-literature
ProteomicsArsenic Trioxide Acts as a Molecular Glue to Promote STUB1-Mediated NPM-ALK Degradation in ALK⁺ ALCL
The NPM-ALK fusion constitutively activates ALK tyrosine kinase, driving oncogenesis in anaplastic large cell lymphoma (ALCL). Although arsenic trioxide (ATO) exhibits therapeutic potential in NPM-ALK⁺ ALCL by inhibiting proliferation and inducing apoptosis, its molecular mechanism remains unclear. ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD073992 | Pride
Deslanoside Ato Targeted protein degradation Npm-alk+ alcl Stub1 Combination therapy 
UnknownMolecular screening of glycyrrhizin-based inhibitors against ACE2 host receptor of SARS-CoV-2.
Not available
S-EPMC8225399 | biostudies-literature
UnknownOntology-based systematical representation and drug class effect analysis of package insert-reported adverse events associated with cardiovascular drugs used in China.
Not available
S-EPMC5653862 | biostudies-literature
UnknownUntargeted Metabolomic Approach to Determine the Regulatory Pathways on Salicylic Acid-Mediated Stress Response in Aphanamixis polystachya Seedlings.
Not available
S-EPMC9102903 | biostudies-literature
ProteomicsArsenic Trioxide Acts as a Molecular Glue to Promote STUB1-Mediated NPM-ALK Degradation in ALK⁺ ALCL
The NPM-ALK fusion constitutively activates ALK tyrosine kinase, driving oncogenesis in anaplastic large cell lymphoma (ALCL). Although arsenic trioxide (ATO) exhibits therapeutic potential in NPM-ALK⁺ ALCL by inhibiting proliferation and inducing apoptosis, its molecular mechanism remains unclear. ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD074054 | Pride
Karpas299 Ato Targeted protein degradation Npm-alk+ alcl 
MetabolomicsMetabolomics profiling of full extracts of bacterial culture supernatants.
Not available
ORGANISM(S): Bacillus megaterium, Enterococcus faecium 
ST002306 | MetabolomicsWorkbench
MetabolomicsMetabolic study of Rumen and ileum in Yanbian cattle

The high-concentrate feeding mode in intensive ruminant production often induces gastrointestinal dysfunction, characterized by microbial dysbiosis, oxidative stress, and inflammation, which compromise animal health and productivity. Glycerol monodecanoate (GMD), a medium-chain fatty acid derivat...

2025-10-28 | MTBLS13227 | MetaboLights
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