Sort   by:  
 Page size 
ProteomicsControl vs Elp3-deficient mouse myeloid progenitors 6-plex TMT LC-MSMS
6-plex TMT LC-MSMS quantification of proteins in myeloid progenitors (Lineage- Sca1- Kit+ cells) isolated from the bone marrow of 8-12 week old male and female control and Elp3-deficient (Elp3fl/fl vav-iCreT/+) mice. Biological triplicates of each genotype were analyzed, each consisting of 1.10e6 ce...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-26 | PXD010486 | Pride
Elongator Myeloid progenitor Elp3 Trna Hematopoiesis 
TranscriptomicsFra1 silencing in MDA-MB-231 cells
Fra1 silencing in MDA-MB-231 cells
ORGANISM(S): Homo sapiens 
2013-07-24 | E-MTAB-1230 | biostudies-arrayexpress
TranscriptomicsComparison of coding RNA expression in steady-state and in response to IL33 and IL5 stimulation in bone marrow eosinophils from IL5-deficient and wild-type littermates
Aim of the experiment was to assess differences in expression of coding RNA between bone marrow eosinophils arising in IL-5 knock-out mice (C57BL/6-Il5tm1Kopf/J) or wild-type littermates and their response to cytokine stimulation. Bone marrow eosinophils were sorted by FACS submitted to RNA-seq imme...
ORGANISM(S): Mus musculus 
2021-12-17 | E-MTAB-10188 | biostudies-arrayexpress
TranscriptomicsTranscriptomic response to ex vivo IL33 stimulation of blood eosinophils from mepolizumab- or omalizumab-treated patients
Coding RNA expression of blood eosinophils from mepolizumab- or omalizumab-treated patients stimulated ex vivo with IL-33 for 6 hours and of directly processed non-stimulated blood eosinophils from the same samples (paired design)
ORGANISM(S): Homo sapiens 
2021-12-17 | E-MTAB-10189 | biostudies-arrayexpress
TranscriptomicsComparison of coding RNA expression of blood eosinophils from mepolizumab- or omalizumab-treated severe asthmatic patients and from healthy controls
RNA-seq comparison of coding RNA expression in blood eosinophils from patients with severe allergic eosinophilic asthma treated with mepolizumab with those of healthy controls and matched severe asthmatic patients receiving omalizumab.
ORGANISM(S): Homo sapiens 
2021-12-17 | E-MTAB-10190 | biostudies-arrayexpress
TranscriptomicsRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system
Aim of the experiment was to compare the gene expression responses of long-term hematopoietic stem cells (HSCs) and myeloid-restricted progenitors (MyPs) to the hematopoietic cell-restricted deletion of the catalytic subunit Elp3 of the Elongator complex. Since Elp3 deletion resulted in activation o...
ORGANISM(S): Mus musculus 
2020-12-10 | E-MTAB-6992 | biostudies-arrayexpress
TranscriptomicsRNA-seq of the 4 stages of maturation of eosinophils in healthy human bone marrow
Biological triplicates of the 4 stages of eosinophil maturation (from I to IV) were sorted via FACS from human bone marrow and analyzed by RNA-seq to allow studying transcriptomic changes along human eosinophil development.
ORGANISM(S): Homo sapiens 
2025-01-01 | E-MTAB-12894 | biostudies-arrayexpress
TranscriptomicsRNA-seq of the 4 stages of maturation of eosinophils in the murine bone marrow in the steady state and in Interleukin-33- induced eosinophilia
Biological triplicates of the 4 stages of eosinophil maturation (from I to IV) were sorted via FACS from the bone marrow of mice in the steady state and in IL-33 induced eosinophilia, allowing to study the transcriptional changes occurring during eosinophil maturation in both conditions.
ORGANISM(S): Mus musculus 
2025-01-01 | E-MTAB-12874 | biostudies-arrayexpress
TranscriptomicsPolysome profiling analysis of myeloid progenitors of control mice or mice conditionally deficient for Elp3 in the hematopoietic system
Aim of the experiment was to compare the genes enriched in the heavy polysome fraction of myeloid progenitors originating from control Elp3fl/fl mice, and in myeloid progenitors originating from mice that underwent hematopoietic cell-restricted deletion of the catalytic subunit Elp3 of the Elongator...
ORGANISM(S): Mus musculus 
2020-12-10 | E-MTAB-9628 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of mouse wild type and Irf3-deficient inflammatory monocytes in response to alum immunization
Effect of Irf3 deficiency on the response of inflammatory monocytes to immunization with the alum adjuvant
ORGANISM(S): Mus musculus 
2011-08-19 | E-MEXP-2881 | biostudies-arrayexpress
Sort   by:  
 Page size